23 patents
Utility
Placental Tissue Grafts and Improved Methods of Preparing and Using the Same
28 Dec 23
Described herein are tissue grafts derived from the placenta.
John Daniel, Randall Spencer, John Russo, Robert Tofe
Filed: 11 Sep 23
Utility
Lyophilized Perforated Placental Membrane Tissue Grafts
2 Nov 23
A dehydrated, partially perforated, placental tissue allograft that can be used in the treatment of wounds.
Thomas J. Koob, Michelle Massee, Divya Sukumar
Filed: 5 Apr 23
Utility
Placental Tissue Grafts and Improved Methods of Preparing and Using the Same
29 Jun 23
A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts.
John Daniel
Filed: 4 Nov 22
Utility
Meshed Placental Membrane Tissue Grafts
5 May 22
A meshed, dehydrated, placental tissue allograft that can be used in the treatment of wounds.
Adam McQueen, Rick LeVaughn, Thomas J. Koob, Michelle Massee
Filed: 4 Nov 21
Utility
Micronized Placental Tissue Compositions and Methods of Making and Using the Same
28 Apr 22
Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof.
Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
Filed: 10 Jan 22
Utility
Meshed Umbilical Cord Tissue Grafts
23 Dec 21
A meshed, dehydrated, umbilical tissue allograft that can be used in the treatment of wounds.
Adam McQueen, Rick LeVaughn, Thomas J. Koob, Michelle Massee
Filed: 17 Jun 21
Utility
Compositions and Methods of Treatment with Amniotic Fluid
16 Sep 21
The present disclosure provides compositions composed of amniotic fluid and/or modified amniotic fluid, a pharmaceutically acceptable carrier, and optionally a placental tissue graft, micronized placental tissue components, or extracts derived therefrom.
Thomas J. Koob, Michelle Massee
Filed: 27 May 21
Utility
Method for Inducing Angiogenesis
17 Jun 21
Disclosed herewith is a method for inducing angiogenesis using modified placental tissue or an extract thereof to treat conditions other than cardiovascular conditions.
Thomas J. Koob
Filed: 13 Oct 20
Utility
Reinforced Placental Tissue Grafts and Methods of Making and Using the Same
20 May 21
Described herein are tissue grafts derived from the placental tissue that are reinforced with at least one biocompatible mesh.
Thomas J. Koob, Robert Tofe, Elizabeth Chen
Filed: 4 Dec 20
Utility
Methods for Treating Cardiac Conditions
6 May 21
Described herein are compositions and methods of treating a cardiac condition using modified placental tissue or an extract of a placental tissue, capable of recruiting stem cells or promoting healing in vivo and in vitro.
Thomas J. Koob, Hubbard Frank Burrows, III
Filed: 15 Jan 21
Utility
Placental Tissue Grafts And Improved Methods Of Preparing And Using The Same
1 Apr 21
Described herein are tissue grafts derived from the placenta.
John Daniel, Randall Spencer, John Russo, Robert Tofe
Filed: 14 Dec 20
Utility
Placental Tissue Component Compositions for Treatment of Skin Defects and Methods Using Same
1 Apr 21
The present disclosure provides methods of treating defects such as wrinkles or scars via a subdermal injection of placental tissue components.
Rick LeVaughn, Sivakkumar Arjunon, Olivia Taylor
Filed: 30 Nov 20
Utility
Collagen and Micronized Placental Tissue Compositions and Methods of Making and Using the Same
21 Jan 21
Described herein are compositions of collagen and micronized placental tissue components, methods for producing the same and methods for using the same for wound healing, repairing damaged tendons, cosmetic applications and covering biocompatible materials and/or devices.
Thomas J. Koob, Michelle Massee
Filed: 10 Aug 20
Utility
Collagen Fiber Ribbons with Integrated Fixation Sutures and Methods of Making the Same
29 Jul 20
The disclosure describes implantable bioprosthesis and constructs having an implantable woven ribbon with at least one integrated suture.
Thomas J. Koob, Mengyan Li
Filed: 13 Apr 20
Utility
Collagen Reinforced Tissue Grafts
8 Jul 20
This invention is directed to a multi-layered tissue graft comprising a collagen layer and at least one separated and washed placental tissue component and/or umbilical cord component, wherein the collagen is human collagen substantially free of non-human antigens.
Thomas J. Koob
Filed: 18 Mar 20
Utility
Compositions and Methods of Treatment with Amniotic Fluid
29 Apr 20
The present disclosure provides compositions composed of amniotic fluid and/or modified amniotic fluid, a pharmaceutically acceptable carrier, and optionally a placental tissue graft, micronized placental tissue components, or extracts derived therefrom.
Thomas J. Koob, Michelle Massee
Filed: 22 Mar 17
Utility
Non-surgical, Localized Delivery of Compositions for Placental Growth Factors
15 Apr 20
Described herewith are compositions comprising placental growth factors and methods for non-surgical, localized delivery thereof.
Thomas J. Koob, Rebeccah J.C Brown
Filed: 9 Dec 19
Utility
Micronized Placental Tissue Compositions with Optional Sealant and Methods of Making and Using the Same
26 Feb 20
Described herein are compositions composed of micronized placental components and optionally a sealant, and pharmaceutical compositions thereof.
Adam McQueen, Frank Burrows, Thomas Koob
Filed: 30 Oct 19
Utility
Micronized Placental Compositions Comprising a Chelator
18 Dec 19
Provided herein are micronized placental compositions composed of micronized placental tissue component, such as amnion or chorion and/or filler bound to one or more chelating agents, which in turn are optionally bound, reversibly, to pharmacologically active metal ions.
Thomas J. Koob
Filed: 29 Aug 19
Utility
Micronized Placental Tissue Compositions and Methods of Making and Using the Same
11 Dec 19
Described herein are composition composed of micronized placental components and pharmaceutical compositions thereof.
Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
Filed: 23 Jul 19