6 patents
Utility
Optimization of Enzyme Replacement Therapy for Treatment of Homocystinuria
9 Feb 23
The present invention provides a method of PEGylating a human truncated cystathionine β-synthase protein containing a mutation of a cysteine to a serine at amino acid position 15 (htCBS C15S).
Tomas Majtan, Jan P. Kraus, Erez M. Bublil, Frank Glavin, Marcia Sellos-Moura
Filed: 5 Apr 22
Utility
Cystathionine Beta-synthase Enzyme Therapy for Treatment of Elevated Homocysteine Levels
15 Sep 22
The present disclosure provides methods for treating homocystinuria or elevated homocysteine levels in subjects, including methods of improving cognitive function and ameliorating skeletal fragility, and methods of stratifying patient populations to determine disease progression or severity and/or to determine treatment regimens.
Marcia SELLOS-MOURA, Erez Moshe BUBLIL, Frank GLAVIN
Filed: 3 Sep 20
Utility
Biphenyl Sulfonamide Compounds for the Treatment of Kidney Diseases or Disorders
9 Sep 20
Radko Komers, Alvin Shih
Filed: 21 May 20
Utility
Biphenyl Sulfonamide Compounds for the Treatment of Type IV Collagen Diseases
13 May 20
Radko Komers, Celia Jenkinson
Filed: 2 Oct 19
Utility
Solid Fosmetpantotenate Formulations
22 Apr 20
Dainius Macikenas, Kale Ruby
Filed: 6 Feb 18
Utility
Pantetheine Derivatives for the Treatment of Neurologic Disorders
6 Nov 19
Maria Beconi, Daniel Elbaum, Savina Malancona
Filed: 23 Jul 17
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