6 patents
Utility
Fatty Acid Acetylated Salicylates and Their Uses
10 Jun 21
The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.
Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Jesse J. Smith
Filed: 2 Jul 20
Utility
Edasalonexent Dosing Regimen for Treating Muscular Dystrophy
28 Jan 21
The invention provides methods and compositions for treating a muscular dystrophy, e.g., Duchenne muscular dystrophy (DMD), in a subject, with a fatty acid acetylated salicylate, e.g., edasalonexent, effective to achieve a threshold plasma concentration of the fatty acid acetylated salicylate in the subject, e.g., a threshold plasma concentration of at least about 20 ng/ml for least 12 hours in a 24 hour period.
Andrew J. Nichols, Michael Perlman
Filed: 5 Nov 18
Utility
Combination Therapies for Treating Muscular Dystrophy
12 Aug 20
The present disclosure relates to methods of treating Duchenne's Muscular Dystrophy by administering an antisense oligonucleotide that induces exon skipping and a non-steroidal anti-inflammatory compound.
Marco A. PASSINI, Jill C. MILNE, Andrew J. NICHOLS
Filed: 27 Sep 18
Utility
Combination Therapies for Treating Muscular Dystrophy
5 Aug 20
The present disclosure relates to methods of treating Duchenne's Muscular Dystrophy by administering an antisense oligonucleotide that induces exon skipping and a non-steroidal anti-inflammatory compound.
Marco A. PASSINI, Jill C. MILNE, Andrew J. NICHOLS
Filed: 27 Sep 18
Utility
Fatty Acid Acetylated Salicylates and Their Uses
12 Feb 20
The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.
Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Jesse J. Smith
Filed: 13 Mar 19
Utility
Fatty Acid Cysteamine Conjugates and Their Use As Activators of Autophagy
5 Feb 20
The invention relates to fatty acid cysteamine conjugates, compositions comprising a fatty acid cysteamine conjugate, and methods for using such conjugates and compositions to treat disease, such as a disease caused by dysregulation of autophagy.
Chi B. Vu, Michael R. Jirousek
Filed: 7 Apr 19
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