74 patents
Utility
Systems and Methods for Producing Sterile Injection Devices
28 Dec 23
The present disclosure provides novel processes for providing sterile, pre-filled syringes or injection devices for pharmaceutical compositions, including protein and biopharmaceutical formulations.
Wendy SHIEU, Gerald LLORACH
Filed: 11 Sep 23
Utility
Systems and methods for producing sterile injection devices
12 Sep 23
The present disclosure provides novel processes for providing sterile, pre-filled syringes or injection devices for pharmaceutical compositions, including protein and biopharmaceutical formulations.
Wendy Shieu, Gerald Llorach
Filed: 21 May 21
Utility
PPARy AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY
13 Jul 23
Barbara Finck, David E. Weinstein, Sarita K. Jain
Filed: 7 Jan 22
Utility
Systems and Methods for Producing Sterile Injection Devices
29 Jun 23
The present disclosure provides novel processes for providing sterile, pre-filled syringes or injection devices for pharmaceutical compositions, including protein and biopharmaceutical formulations.
Wendy SHIEU, Gerald LLORACH
Filed: 21 May 21
Utility
Stable protein compositions and methods of their use
21 Feb 23
The present invention is directed to compositions and methods for stabilizing a protein without a surfactant.
Jun Liu, Mark Manning, Isaias Prado
Filed: 28 Oct 16
Utility
Method of filling a container with no headspace
14 Feb 23
The present invention is directed to methods for filling a container wherein the filled container has no headspace.
John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning
Filed: 17 Jun 21
Utility
Control Mechanism for Priming an Injection Device
27 Oct 22
An injection device includes a syringe barrel for holding medication, a collar positioned on a proximal end of the syringe barrel, a piston assembly including a piston arranged in the syringe barrel, and a rod member extending through the collar to the piston, and a blocking member arranged on the rod member.
Alasdair George Young, Gerald Llorach, Su Ann Teh, Dmitry Soyfertis, Brian Tachibana
Filed: 2 Oct 20
Utility
Compositions and Methods to Treat Non-alcoholic Fatty Liver Diseases (Nafld)
15 Sep 22
Provided herein are methods and combination therapies useful for the treatment of non-alcoholic fatty liver diseases (NAFLD).
Christos Mantzoros, Glenn D. Rosen
Filed: 27 Dec 19
Utility
Compositions and Methods to Treat Non-alcoholic Fatty Liver Diseases (Nafld)
15 Sep 22
Provided herein are methods and combination therapies useful for the treatment of non-alcoholic fatty liver diseases (NAFLD).
Christos Mantzoros, Glenn D. Rosen
Filed: 27 Dec 19
Utility
Stable aqueous formulations of aflibercept
30 Aug 22
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of aflibercept, wherein the formulation is free of organic co-solvent and/or free of buffer; methods for making such a formulation; and methods of using such a formulation.
Jun Liu, Mark Manning, Sekhar R. Kanapuram
Filed: 10 Sep 19
Utility
Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
2 Aug 22
The present invention relates to methods for treating a disease associated with insulin resistance selected from a nonalcoholic fatty liver disease (NAFLD) and its sequelae, a lipodystrophic syndrome or a combination thereof with the selective PPARγ agonist, INT131 and optionally vitamin E or compositions thereof.
Christos Mantzoros
Filed: 25 Jun 20
Utility
Methods for making recombinant proteins
26 Jul 22
The present invention provides methods and compositions for making proteins, preferably antibodies, more preferably anti-tumor necrosis factor alpha antibodies, and most preferably adalimumab.
Elzbieta Wiktoria Puchacz
Filed: 9 Sep 19
Utility
Compositions and Methods to Treat Cancer
30 Jun 22
Glenn D. Rosen
Filed: 26 May 20
Utility
Method of Producing a Recombinant Protein
23 Jun 22
Provided herein are methods of producing a recombinant protein that include fed-batch culturing a mammalian cell.
Robin Modi, James Russell Grove
Filed: 1 May 20
Utility
Compositions and Methods to Treat Non-alcoholic Fatty Liver Diseases (Nafld)
23 Jun 22
Provided herein are methods and combination therapies useful for the treatment of non-alcoholic fatty liver diseases (NAFLD).
Christos Mantzoros
Filed: 27 Dec 19
Utility
Compositions and Methods to Treat Non-alcoholic Fatty Liver Diseases (Nafld)
23 Jun 22
Provided herein are methods and combination therapies useful for the treatment of non-alcoholic fatty liver diseases (NAFLD).
Christos Mantzoros, Glenn D. Rosen
Filed: 27 Dec 19
Utility
Compositions and Methods to Treat Non-alcoholic Fatty Liver Diseases (Nafld)
9 Jun 22
Provided herein are methods and combination therapies useful for the treatment of non-alcoholic fatty liver diseases (NAFLD).
Christos Mantzoros, Glenn D. Rosen
Filed: 27 Dec 19
Utility
Compositions and Methods to Treat Non-alcoholic Fatty Liver Diseases (Nafld)
12 May 22
Provided herein are methods and combination therapies useful for the treatment of non-alcoholic fatty liver diseases (NAFLD).
Christos Mantzoros, Glenn D. Rosen
Filed: 27 Dec 19
Utility
PPARy agonist for treatment of progressive supranuclear palsy
22 Feb 22
Barbara Finck, David E. Weinstein, Sarita K. Jain
Filed: 3 Apr 18
Utility
Method of Filling a Container with No Headspace
10 Feb 22
The present invention is directed to methods for filling a container wherein the filled container has no headspace.
John Ogez, Jun Liu, Wenchang Ji, Patrick Daniel Begley, Isaias Prado, Mark Manning
Filed: 17 Jun 21