7 patents
Utility
Aggregating microparticles for medical therapy
31 Jan 23
The present invention is a surface treated drug-loaded solid (e.g., non-porous) microparticle that aggregates in vivo to form a consolidated larger particle for medical therapy.
Yun Yu, Joshua Kays, Ming Yang, Jeffrey L. Cleland
Filed: 10 Sep 19
Utility
Drugs and compositions for the treatment of ocular disorders
10 Jan 23
The present invention provides new prodrugs of therapeutically active compounds, including oligomeric prodrugs, and compositions to treat medical disorders, for example glaucoma, a disorder or abnormality related to an increase in intraocular pressure (IOP), a disorder requiring neuroprotection, age-related macular degeneration, or diabetic retinopathy.
Ming Yang, John G. Bauman, Jeffrey L. Cleland, Nu Hoang, Emmett Cunningham
Filed: 20 Sep 19
Utility
Equatorially modified polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates
9 Aug 22
Embodiments of the invention are directed to new equatorially modified polymer linked multimers of guanosine-3′, 5′-cyclic monophosphate (cGMP) analogues that inhibit the cGMP-signaling system.
Hans-Gottfried Genieser, Frank Schwede, Andreas Rentsch, Per Ekström, Valeria Marigo, Francois Paquet-Durand
Filed: 29 Jun 17
Utility
Aggregating microparticles for medical therapy
17 May 22
The present invention is a surface treated drug-loaded solid (e.g., non-porous) microparticle that aggregates in vivo to form a consolidated larger particle for medical therapy.
Yun Yu, Joshua Kays, Ming Yang, Jeffrey L. Cleland
Filed: 10 Sep 19
Utility
Extended release microparticles and suspensions thereof for medical therapy
2 Nov 21
An improved microparticle or lyophilized or otherwise reconstitutable microparticle composition thereof for medical therapy, including ocular therapy.
Ming Yang, Jeffrey L. Cleland, Yun Yu, Weiling Yu, Joshua Kays
Filed: 10 May 18
Utility
Compounds and compositions for the treatment of ocular disorders
25 Nov 19
The disclosure describes prodrugs and derivatives of prostaglandins, carbonic anhydrase inhibitors, kinase inhibitors, beta-adrenergic receptor antagonists and other drugs, as well as controlled delivery formulations containing such prodrugs and derivatives, for the treatment of ocular disorders.
Jeffrey L. Cleland, Ming Yang, John G. Bauman, Nu Hoang, Emmett Cunningham
Filed: 15 Oct 18
Utility
Aggregating microparticles for medical therapy
14 Oct 19
The present invention is a surface treated drug-loaded solid (e.g., non-porous) microparticle that aggregates in vivo to form a consolidated larger particle for medical therapy.
Yun Yu, Joshua Kays, Ming Yang, Jeffrey L. Cleland
Filed: 10 Nov 16
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