8 patents
Utility
Protocol to Minimize Calcineurin Inhibitor Nephrotoxicity
30 Nov 23
Provided herein are methods of employing pharmacodynamics regimens to maximize effectiveness of voclosporin in treatment of proteinuric kidney diseases while minimizing undesirable side effects, such as but not limited to calcineurin inhibitor nephrotoxicity.
Michael Martin, Robert B. Huizinga, Neil Solomons
Filed: 28 Jul 23
Utility
Protocol for treatment of lupus nephritis
11 Apr 23
By employing a pharmacodynamic dosing regimen, the effectiveness of a protocol for treatment of a proteinuric kidney disease with voclosporin can be maximized while minimizing undesirable side effects.
Neil Solomons, Robert B. Huizinga
Filed: 4 Apr 22
Utility
Protocol for Treatment of Lupus Nephritis
21 Jul 22
By employing a pharmacodynamic dosing regimen, the effectiveness of a protocol for treatment of a proteinuric kidney disease with voclosporin can be maximized while minimizing undesirable side effects.
Neil SOLOMONS, Robert B. HUIZINGA
Filed: 4 Apr 22
Utility
Ophthalmic Compositions
4 Nov 21
The embodiments disclosed herein relate to ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors, and more particularly to methods for treating an ocular disease and/or condition using the disclosed compositions.
Ashim K. MITRA, Poonam R. VELAGALETI, Subramanian NATESAN
Filed: 12 Apr 21
Utility
Ophthalmic compositions
13 Apr 21
The embodiments disclosed herein relate to ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors, and more particularly to methods for treating an ocular disease and/or condition using the disclosed compositions.
Ashim K. Mitra, Poonam R. Velagaleti, Subramanian Natesan
Filed: 8 Feb 19
Reissue
Cyclosporine analogue mixtures and their use as immunomodulating agents
28 Sep 20
The invention is directed to isomeric mixtures of cyclosporine analogues that are structurally similar to cyclosporine A.
Selvaraj A. Naicker, Randall W Yatscoff, Robert T Foster
Filed: 29 Jun 14
Utility
Ophthalmic Compositions
8 Jan 20
The embodiments disclosed herein relate to ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors, and more particularly to methods for treating an ocular disease and/or condition using the disclosed compositions.
Ashim K. Mitra, Poonam R. Velagaleti, Subramanian Natesan
Filed: 7 Feb 19
Utility
Cyclosporine analogue mixtures and their use as immunomodulating agents
11 Nov 19
The invention is directed to isomeric mixtures of cyclosporine analogues that are structurally similar to cyclosporine A.
Selvaraj A. Naicker, Randall W Yatscoff, Robert T Foster
Filed: 13 Aug 17
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