9 patents
Utility
Administration of an Anti-activin-a Compound to a Subject
29 Jun 23
The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor.
Huiquan HAN, Christopher Michael HAQQ, Isaac CIECHANOVER, Xiaolan ZHOU, John Zhao-Nian LU
Filed: 22 Dec 22
Utility
Car T Cells That Target Aspergillus-associated Antigens
12 Jan 23
Provided herein are compositions and methods for targeted treatment of Aspergillus-associated diseases and disorders in mammals, such as diseases and disorders associated with Aspergillus infection.
Blake Tolu Aftab
Filed: 7 Dec 20
Utility
Administration of an anti-activin-A compound to a subject
3 Jan 23
The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor.
Huiquan Han, Christopher Michael Haqq, Isaac Ciechanover, Xiaolan Zhou, John Zhao-Nian Lu
Filed: 13 Dec 19
Utility
Antigen Specific CD19-TARGETED Car-t Cells
3 Nov 22
Disclosed are compositions and methods for targeted treatment of cancer, such as hematologic cancer.
Blake T. Aftab
Filed: 29 Apr 20
Utility
Methods of Managing Tumor Flare In Adoptive Immunotherapy
23 Dec 21
Provided herein are methods of treating a solid malignant tumor using antigen-specific T cells and methods of managing tumor flare in treatment of a solid malignant tumor using antigen-specific T cells.
Robert Baiocchi
Filed: 22 Oct 18
Utility
Methods for Expanding Antigen-specific Car-t Cells, Compositions and Uses Related Thereto
30 Sep 21
Provided herein are methods for preparing and characterizing CAR-T cell cultures and preparations.
Blake T. Aftab, Christina Pham, Rhine Shen, Michelle Wu
Filed: 10 Sep 19
Utility
Systems and Methods for Distributing Cell Therapies
4 Nov 20
The disclosure relates to delivery systems, and corresponding methods, for selecting and delivering an allogeneic T-cell line for administration to a patient, e.g., according to the HLA profile of the patient's somatic or diseased cells.
Derrell D. Porter
Filed: 6 Jan 19
Utility
Immunotherapy for Polyomaviruses
24 Jun 20
Provided herein are methods and compositions related to polyomavirus epitopes useful in the treatment of cancer or a polyomavirus infection.
Rajiv Khanna, George Robin Ambalathinga Thomas, Blake Tolu Aftab
Filed: 7 Sep 17
Utility
Methods of Treating Multiple Sclerosis Using Autologous T Cells
20 Nov 19
Provided herein are compositions and methods related to the treatment of multiple sclerosis in a subject.
Rajiv Khanna, Corey Smith, Blake T. Aftab
Filed: 18 Jan 18
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