2 patents
Utility
Delivery of biomolecules to PBMCs to modify an immune response
4 Jul 23
The present application provides peripheral blood mononuclear cells comprising an antigen, methods of manufacturing such PBMCs, and methods of using such PBMCs, such as for modulating an immune response in an individual.
Armon R. Sharei, Howard Bernstein, Scott Loughhead, Matthew Booty, Katarina Blagovic, Kelan Hlavaty, Defne Yarar, Emrah Ilker Ozay, Carolyne Kelly Smith
Filed: 27 Feb 20
Utility
Intracellular delivery of biomolecules to cells comprising a cell wall
28 Mar 23
The present disclosure pertains to methods for delivering a compound into a cell comprising a cell wall, including passing a cell suspension through a constriction, wherein said constriction deforms the cell comprising a cell wall, thereby causing a perturbation of the cell such that the compound enters the cell, wherein said cell suspension is contacted with the compound.
Armon R. Sharei, Howard Bernstein, Jonathan B. Gilbert
Filed: 2 Sep 16
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