6 patents
Utility
Mitochondrial Dna Deletions Associated with Endometriosis
11 Aug 22
Aberrant mitochondrial DNA (mtDNA) molecules having specific large-scale deletions and having an association with endometriosis are provided.
Jennifer CREED, Andrea MAGGRAH, Brian REGULY, Andrew HARBOTTLE, Robert USHER
Filed: 20 Dec 19
Utility
3.4 KB mitochondrial DNA deletion for use in the detection of cancer
7 Sep 21
A method is provided for detecting a cancer in an individual, the method comprising detection of a deletion in the nucleic acid sequence between residues 10743 and 14125 in mitochondrial DNA by extracting the mitochondrial DNA (mtDNA) from the biological sample obtained from the individual and quantifying the amount of mtDNA in the sample having a deletion in the nucleic acid sequence between approximately residues 10743 and 14125 of the mtDNA genome, and comparing the amount of mtDNA in the sample having the deletion to at least one known reference sample.
Ryan L. Parr, Robert Thayer, Gabriel D. Dakubo, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Brian Reguly
Filed: 3 Jun 19
Utility
Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
2 Feb 21
Mitochondrial DNA deletions useful for the detection of cancers and sun exposure are provided.
Ryan L. Parr, Robert Thayer, Gabriel Dakubo, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Brian Reguly, Andrew Harbottle, Mark Birch-Machin
Filed: 29 Aug 17
Utility
Mitochondrial DNA deletion between about residues 12317-16254 for use in the detection of cancer
18 Dec 19
Methods and kits for predicting, diagnosing and monitoring cancer, wherein the methods comprise quantifying mitochondrial DNA mutations in biological samples.
Ryan Parr, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Katrina Maki, Gabriel Dakubo, Brian Reguly, Andrew Harbottle, Jude Alexander
Filed: 31 Aug 19
Utility
Aberrant Mitochondrial Dna, Associated Fusion Transcripts and Hybridization Probes Therefor
18 Dec 19
The present invention provides novel mitochondrial fusion transcripts and the parent mutated mtDNA molecules that are useful for predicting, diagnosing and/or monitoring cancer.
Ryan Parr, Brian Reguly, Gabriel Dakubo, Jennifer Creed, Kerry Robinson
Filed: 16 Apr 19
Utility
3.4 KB Mitochondrial Dna Deletion for Use In the Detection of Cancer
23 Oct 19
A method is provided for detecting a cancer in an individual, the method comprising detection of a deletion in the nucleic acid sequence between residues 10743 and 14125 in mitochondrial DNA by extracting the mitochondrial DNA (mtDNA) from the biological sample obtained from the individual and quantifying the amount of mtDNA in the sample having a deletion in the nucleic acid sequence between approximately residues 10743 and 14125 of the mtDNA genome, and comparing the amount of mtDNA in the sample having the deletion to at least one known reference sample.
Ryan L. PARR, Robert THAYER, Gabriel D. DAKUBO, Jennifer CREED, Kerry ROBINSON, Andrea MAGGRAH, Brian REGULY
Filed: 2 Jun 19
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