65 patents
Page 3 of 4
Utility
Anti-tau Antibodies and Methods of Use
29 Apr 21
The invention provides anti-Tau antibodies and methods of using the same.
Oskar Adolfsson, Isidro Hotzel, Danielle DiCara
Filed: 5 Jun 20
Utility
Anti-abeta Therapeutic Vaccines
1 Apr 21
A liposomal vaccine composition comprises a β-amyloid (Aβ)-derived peptide antigen displayed on the surface of the liposome.
Emma Fiorini, Marija Vukicevic Verhille, Maria Pihlgren Bosch
Filed: 6 Nov 20
Utility
Diagnostic Compositions for Pet Imaging, a Method for Manufacturing the Diagnostic Composition and Its Use In Diagnostics
18 Feb 21
Johnny CASTILLO MELEAN, Thomas BETZEL, Mathias BERNDT, Hanno SCHIEFERSTEIN, Heiko KROTH, Jérôme MOLETTE, Vincent DARMENCY, Emanuele GABELLIERI
Filed: 22 Jan 19
Utility
Gamma-carboline Compounds for the Detection of Tau Aggregates
18 Feb 21
Mathias BERNDT, Andre MÜLLER, Felix ODEN, Hanno SCHIEFERSTEIN, Heribert SCHMITT-WILLICH, Heiko KROTH, Jérôme MOLETTE
Filed: 22 Jan 19
Utility
Azacarboline Compounds for the Detection of Tau Aggregates
11 Feb 21
Mathias BERNDT, Andre MÜLLER, Felix ODEN, Hanno SCHIEFERSTEIN, Heribert SCHMITT-WILLICH, Heiko KROTH, Jérôme MOLETTE, Emanuele GABELLIERI, Cédric BOUDOU
Filed: 22 Jan 19
Utility
Novel Method of Preparing an Imaging Compound
11 Feb 21
The present invention relates to a novel method of preparing a compound of the formula I.
Marion ZERNA, Mathias BERNDT, Hanno SCHIEFERSTEIN, Johnny CASTILLO MELEAN, Heiko KROTH, Jérôme MOLETTE, Vincent DARMENCY, Emanuele GABELLIERI
Filed: 22 Jan 19
Utility
Compounds for imaging Tau protein aggregates
14 Dec 20
Heiko Kroth, Jérôme Molette, Hanno Schieferstein, Andre Müller, Heribert Schmitt-Willich, Mathias Berndt, Felix Oden
Filed: 20 Jul 17
Utility
Compositions of phosphorylated tau peptides and uses thereof
2 Dec 20
Liposomes containing tau peptides, preferably phosphorylated tau peptides, and conjugates containing tau peptides, preferably phosphorylated tau peptides, conjugated to an immunogenic carrier are described.
Elizabeth Anne RAMSBURG, Donata DE MARCO, Anish CHAKKUMKAL, Charlotte SADAKA, Jaap GOUDSMIT, Andreas MUHS, Maria PIHLGREN BOSCH, Marija VUKICEVIC VERHILLE, David HICKMAN, Nicolas PIOT, Saroj Raj GHIMIRE
Filed: 23 Oct 18
Utility
Compounds for imaging Tau protein aggregates
16 Nov 20
Heiko Kroth, Jérôme Molette, Vincent Darmency, Hanno Schieferstein, Andre Müller, Heribert Schmitt-Willich, Mathias Berndt, Felix Oden, Emanuele Gabellieri
Filed: 20 Jul 17
Utility
Anti-Tau antibodies and methods of use
16 Nov 20
The invention provides anti-Tau antibodies and methods of using the same.
Oskar Adolfsson, Kristin Ruth Wildsmith, Marcel Van Der Brug, Andreas Muhs
Filed: 22 May 19
Utility
Anti-abeta therapeutic vaccines
9 Nov 20
A liposomal vaccine composition comprises a β-amyloid (Aβ)-derived peptide antigen displayed on the surface of the liposome.
Emma Fiorini, Marija Vukicevic Verhille, Maria Pihlgren Bosch
Filed: 8 Apr 19
Utility
Heterologous Administration of Tau Vaccines
28 Oct 20
Methods for inducing an immune response against tau protein in a subject suffering from a neurodegenerative disease, disorder or condition, such as Alzheimer's Disease, are described.
Elizabeth Anne RAMSBURG, Donata DE MARCO, Anish CHAKKUMKAL, Charlotte SADAKA, Jaap GOUDSMIT, Andreas MUHS, Maria PIHLGREN BOSCH, Marija VUKICEVIC VERHILLE, David HICKMAN, Nicolas PIOT, Saroj Raj GHIMIRE
Filed: 22 Apr 20
Utility
Bicyclic Compounds for Diagnosis and Therapy
23 Sep 20
The present invention relates to novel compounds that can be employed in the diagnosis, monitoring of disease progression or monitoring of drug activity, of a group of disorders and abnormalities associated with alpha-synuclein (α-synuclein, A-synuclein, aSynuclein, A-syn, α-syn, aSyn) aggregates including, but not limited to, Lewy bodies and/or Lewy neurites, such as Parkinson's disease.
Jérôme Molette, Emanuele Gabellieri, Vincent Darmency
Filed: 4 Jun 20
Utility
Method of Safe Administration of Phosphorylated Tau Peptide Vaccine
12 Aug 20
Methods for inducing anti-phosphorylated Tau antibodies without inducing a severe adverse event in humans are described.
Andrea PFEIFER, Andreas MUHS, Maria PIHLGREN BOSCH, Marija VUKICEVIC VERHILLE, Nicolas PIOT, Saroj Raj GHIMIRE, Elizabeth Anne RAMSBURG, Donata DE MARCO, Charlotte SADAKA
Filed: 6 Feb 20
Utility
Anti-Tau antibodies and methods of use
13 Jul 20
The invention provides anti-Tau antibodies and methods of using the same.
Oskar Adolfsson, Isidro Hotzel, Danielle DiCara
Filed: 22 May 19
Utility
Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins
25 May 20
The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease.
Heiko Kroth, Sreenivasachary Nampally, Jér{hacek over (o)}me Molette, Emanuele Gabellieri, Pascal André René Benderitter, Wolfgang Froestl, Hanno Schieferstein, Andre Mueller, Heribert Schmitt-Willich, Mathias Berndt
Filed: 20 Jan 15
Utility
Novel compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates
13 May 20
The present invention relates to novel compounds that can be employed in the treatment, alleviation or prevention of a group of disorders and abnormalities associated with Tau (Tubulin associated unit) protein aggregates including, but not limited to, Neurofibrillary Tangles (NFTs), such as Alzheimer's disease (AD).
Sreenivasachary NAMPALLY, Emanuele GABELLIERI, Jerome MOLETTE
Filed: 8 Jan 20
Utility
Compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates
27 Apr 20
The present invention relates to novel compounds that can be employed in the treatment, alleviation or prevention of a group of disorders and abnormalities associated with Tau (Tubulin associated unit) protein aggregates including, but not limited to, Neurofibrillary Tangles (NFTs), such as Alzheimer's disease (AD).
Sreenivasachary Nampally
Filed: 12 Mar 19
Utility
Anti-tau antibodies and methods of use
27 Apr 20
The invention provides anti-Tau antibodies and methods of using the same.
Oskar Adolfsson, Gai Ayalon, Isidro Hotzel, Danielle Marie Di Cara
Filed: 6 May 19
Utility
Humanized Antibody
19 Feb 20
The present invention is related to chimeric and humanized antibody and to methods and compositions for the therapeutic and diagnostic use in the treatment of amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease.
Andrea Pfeifer, Maria Pihlgren, Andreas Muhs, Ryan Watts
Filed: 31 Mar 19