18 patents
Utility
Methods and compounds for restoring mutant p53 function
14 Nov 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li, Bruce Fahr, Andrew Good
Filed: 22 Sep 20
Utility
Methods and compounds for restoring mutant p53 function
7 Nov 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li, Bruce Fahr, Andrew Good
Filed: 11 May 21
Utility
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
5 Oct 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh VU, Romyr DOMINIQUE, Hongju LI, Bruce FAHR, Andrew GOOD
Filed: 2 Jun 23
Utility
DEUTERATED COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
28 Sep 23
The compounds of the current disclosure include propynyl substituted indoles, where one or more hydrido radicals is substituted with a deuterium atom, wherein the compound binds a mutant p53 protein and increases wild-type p53 activity of the mutant p53 protein.
Binh VU
Filed: 26 Jan 23
Utility
Methods and compounds for restoring mutant p53 function
22 Aug 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li, Bruce Fahr, Yi Chen
Filed: 22 Jun 21
Utility
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
23 Feb 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh VU, Romyr DOMINIQUE, Hongju LI, Bruce FAHR, Yi CHEN
Filed: 22 Jun 21
Utility
Methods and Compounds for Restoring Mutant P53 Function
16 Feb 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Arnold Levine, David Mack, Binh Vu, Thomas Davis, Melissa Dumble
Filed: 15 Jun 21
Utility
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
16 Feb 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li, Bruce Fahr, Yi Chen
Filed: 21 Jun 21
Utility
Companion Diagnostic Tool for Mutant P53 Reactivating Compounds
9 Feb 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Melissa Dumble
Filed: 18 Jun 21
Utility
Combination Therapy for Treatment of Cancer
2 Feb 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Arnold Levine, Melissa Dumble
Filed: 15 Jun 21
Utility
Uses of P53 X-ray Co-crystal Structures
26 Jan 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh VU, Andrew GOOD
Filed: 18 Jun 21
Utility
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
5 Jan 23
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li, Bruce Fahr, Andrew Good
Filed: 11 May 21
Utility
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
6 Oct 22
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh VU, Romyr DOMINIQUE, Hongju LI, Bruce FAHR, Andrew GOOD
Filed: 22 Sep 20
Utility
Methods and compounds for restoring mutant p53 function
24 May 22
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li
Filed: 16 Mar 20
Utility
Compositions and Methods Utilizing Genetically-modified Animals and Cells
30 Dec 21
Provided herein are compositions and methods for studying cancer therapeutics and etiology, for example, mouse cancer models, cancer cell lines, and uses thereof.
Arnold Levine, David Mack, Anna Puzio-Kuter, Lizhong Xu, Thomas W. Davis, Melissa Dumble
Filed: 24 Jun 21
Utility
Methods for Detecting Mutant P53 Function
30 Dec 21
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Arnold LEVINE, Jonathan OLINER, Thomas W. DAVIS, Mary Kate McBRAYER
Filed: 22 Jun 21
Utility
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
6 Jan 21
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li
Filed: 15 Mar 20
Utility
Methods and compounds for restoring mutant p53 function
4 May 20
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer.
Binh Vu, Romyr Dominique, Hongju Li
Filed: 17 Oct 18
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