195 patents
Page 4 of 10
Utility
Use of Inhibitors of Yap/taz for the Treatment of Cancer
28 Jul 22
Methods of treating or preventing cancer, or treating or preventing noncancerous tumors or lesions, in a subject in need thereof.
Chunling Yi, Shannon M. White, Jeffrey Field
Filed: 26 Apr 20
Utility
Generating Hypotheses In Data Sets
23 Jun 22
A method for generating hypotheses in a corpus of data comprises selecting a form of ontology; coding the corpus of data based on the form of the ontology; generating ontology space based on coding results and the ontology; transforming the ontology space into a hypothesis space by grouping hypotheses; weighing hypotheses included in the hypothesis space; and applying a science-based optimization algorithm configured to model a science-based treatment of the weighted hypotheses.
Ophir Frieder, David Hartley
Filed: 28 Jul 21
Utility
Large Dzyaloshinskii-Moriya Interaction and Perpendicular Magnetic Anisotrophy Induced by Chemisorbed Species on Ferromagnets
23 Jun 22
Embodiments may provide a realization of strong Dzyaloshinskii-Moriya interaction (DMI) and perpendicular magnetic anisotropy (PMA) induced by chemisorbed species on a ferromagnetic layer.
Kai Liu, Gong Chen, Andreas Schmid
Filed: 14 Mar 22
Utility
Methods for treating cancer
14 Jun 22
The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy.
Robert D. Arbeit, Paula Marie Ragan, Michael B. Atkins, James W. Mier, David McDermott
Filed: 14 Dec 16
Utility
Drug Inhibitor Against Migration and Invasion of Cancer Cells and Methods of Treating Against Metastasis of Cancer Cells
2 Jun 22
Hemayet ULLAH, Sivanesan DAKSHANAMURTHY
Filed: 25 Mar 20
Utility
Radiation mitigator and method of use thereof
26 Apr 22
Milton L. Brown, Yali Kong, Courtney Houchen, Sripathi M. Sureban, Parthasarathy Chandrakesan
Filed: 31 Mar 17
Utility
Enhancing chemotherapy in medulloblastoma and glioblastoma with high basal p53 levels
26 Apr 22
Provided herein is a method of treating medulloblastoma or glioblastoma in a subject by administering to the subject a PI3K activator (e.g., thymosin β-4 or a derivative thereof) and one or more chemotherapeutic agents and/or radiation.
Christopher Albanese, Aisha Naeem
Filed: 12 Mar 19
Utility
Quantitative Auxiliary-free Chirality Sensing with a Metal Probe
14 Apr 22
The present invention relates to an analytical method that includes providing a sample potentially containing a chiral analyte that can exist in stereoisomeric forms, and providing a probe selected from the group consisting of metal salts.
Christian WOLF, Zeus A. O. DE LOS SANTOS, Ciaran LYNCH
Filed: 11 Sep 19
Utility
Systems and Methods for Identifying and Isolating Invasive Subpopulations of Cancer Cells In Real-time
14 Apr 22
Systems and methods for characterizing cancer cells are disclosed.
Anton Wellstein, Ghada M. Sharif, Makarand Paranjape, Leon Der
Filed: 9 Sep 19
Utility
Method and System for Assessing Drug Efficacy Using Multiple Graph Kernel Fusion
14 Apr 22
Embodiments of the present systems and methods may provide techniques to predict the success or failure of a drug used for disease treatment.
Ophir Frieder, Hao-Ren Yao, Der-Chen Chang
Filed: 20 Dec 21
Utility
Enhancing the legibility of images using monochromatic light sources
5 Apr 22
A system and method are described for enhancing readability of document images by operating on each document individually.
Ophir Frieder, Gideon Frieder, Jon Parker
Filed: 26 May 20
Utility
Methods for Treating Virus Infection or Proliferation
31 Mar 22
Hemayet ULLAH, Sivanesan DAKSHANAMURTHY
Filed: 29 Oct 19
Utility
Use of methadone metabolites for treatment of anxiety and depression
22 Mar 22
Previous studies (Xiao et al., 2001) have identified two metabolites of methadone, EMDP (2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline) and EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine), which are considered to be inactive at opiate receptors, as relatively potent noncompetitive channel blockers of α3β4 nAChRs.
Kenneth J. Kellar, Yingxian Xiao, Patrick A. Forcelli
Filed: 13 Jul 20
Utility
Treating cancer with a CCK receptor inhibitor and an immune checkpoint inhibitor
22 Mar 22
Provided herein are methods for treating a cholecystokinin (CCK) receptor-expressing cancerous tumor in a subject.
Jill P. Smith, Louis Weiner, Sandra Jablonski, Sandeep Nadella, Shangzi Wang
Filed: 15 Mar 18
Utility
Metabolic biomarkers for cognitive ability
22 Mar 22
The present invention relates to methods of determining if a subject has a decreased risk of suffering from future memory impairment.
Mark E. Mapstone, Howard J. Federoff, Massimo S. Fiandaca, Amrita K. Cheema
Filed: 2 Feb 18
Utility
Predictive Biomarkers for Adverse Effects of Radiation Therapy
3 Mar 22
Methods of treating with radiation therapy a subject having cancer, in which the method comprises administering radiation therapy to the subject.
Anatoly Dritschilo, Amrita K. Cheema, Scott Grindrod, Xiaogang Zhong
Filed: 15 Sep 21
Utility
Nanoparticle to target cancer
15 Feb 22
Jill P. Smith, Stephan Stern, Abdullah Mahmud
Filed: 15 Mar 17
Utility
Harvesting cell-free non-coding RNAS (CFNCRS) from interstitial fluid for sensitive biomarkers
15 Feb 22
A system for determining the presence of cell-free non-coding RNA (cfNCR) biomarkers in interstitial fluid includes a microfluidic device for non-invasively and passively accessing interstitial fluid from a patient.
Makarand Paranjape
Filed: 31 Jan 18
Utility
Method and system for assessing drug efficacy using multiple graph kernel fusion
1 Feb 22
Embodiments of the present systems and methods may provide techniques to predict the success or failure of a drug used for disease treatment.
Ophir Frieder, Hao-Ren Yao, Der-Chen Chang
Filed: 3 Nov 20
Utility
Detecting infection using personalized criteria
25 Jan 22
A triage system that determines whether a user is likely to have contracted a disease based on sensor data received from a user device (e.g., a smartphone or activity tracker).
Howard Federoff, Ophir Frieder
Filed: 18 Aug 20