195 patents
Page 5 of 10
Utility
Process and framework for facilitating information sharing using a distributed hypergraph
18 Jan 22
A knowledge model “overlay” for organizing and analyzing large, dynamic data volumes is implemented as a hypergraph that manifests as a result of a distributed theory-driven data source transformation process.
J. Cory Smart
Filed: 24 May 19
Utility
Apparatus and method for delivery of antimicrobial during a transdermal sampling and delivery process
11 Jan 22
A device for introducing at least one antimicrobial in an exposed region of a user's skin caused while accessing interstitial fluid includes a substrate having thereon at least one electrically controllable microheating element including at least a microheater portion with multiple electrodes connected to the microheater portion for forming a micropore in the user's skin.
Makarand Paranjape, Shruti M. Paranjape
Filed: 2 Aug 16
Utility
Treating Non-alcoholic Steatohepatitis with CCK Inhibitors
6 Jan 22
Provided herein are methods for treating nonalcoholic steatohepatitis (NASH) in a subject, comprising administering to a subject having NASH an effective amount of a CCK receptor inhibitor.
Jill P. SMITH
Filed: 5 Nov 19
Utility
Compositions and Methods for Treating Inflammatory Neurological Disorders
6 Jan 22
The present application is directed to methods and compositions for treating a condition marked by enhanced inflammation in the central nervous system (CNS).
Jeffrey Huang, Maryna Baydyuk
Filed: 2 Oct 19
Utility
CD99 inhibitors and their uses
21 Dec 21
Aykut Üren, Haydar Celik, Jeffrey A. Toretsky
Filed: 12 Oct 17
Utility
Detecting Infection Using Surrogates
9 Dec 21
A triage system that determines whether a user is likely to have contracted a disease based on sensor data received from a user device (e.g., a smartphone or activity tracker).
Howard Federoff, Ophir Frieder
Filed: 19 Aug 21
Utility
Compositions and Methods for Treating Neurodegenerative, Myodegenerative, and Lysosomal Storage Disorders
2 Dec 21
Provided herein are compositions and methods for treating or preventing a neurodegenerative disease, a myodegenerative disease, a prion disease or a lysosomal storage disease in a subject.
Christian WOLF, Balaraman KALUVU, Charbel MOUSSA
Filed: 20 Nov 19
Utility
Treating melanoma with mebendazole and a mitogen-activated kinase inhibitor
23 Nov 21
Provided herein are methods for treating melanoma in a subject.
Sivanesan Dakshanamurthy, Stephen W. Byers, Dean Rosenthal
Filed: 16 Mar 18
Utility
Cache Optimization Via Topics in Web Search Engines
18 Nov 21
Embodiments may provide a cache for query results that can adapt the cache-space utilization to the popularity of the various topics represented in the query stream.
Ophir Frieder, Ida Mele, Raffaele Perego, Nicola Tonellotto
Filed: 21 Jul 21
Utility
Detecting Infection Using Personalized Criteria
4 Nov 21
A triage system that determines whether a user is likely to have contracted a disease based on sensor data received from a user device (e.g., a smartphone or activity tracker).
Howard Federoff, Ophir Frieder
Filed: 18 Aug 20
Utility
Cache optimization via topics in web search engines
19 Oct 21
Embodiments may provide a cache for query results that can adapt the cache-space utilization to the popularity of the various topics represented in the query stream.
Ophir Frieder, Ida Mele, Raffaele Perego, Nicola Tonellotto
Filed: 16 Oct 19
Utility
Targeting Tumor Cells with Chemotherapeutic Agents Conjugated to Anti-matriptase Antibodies by In Vivo Cleavable Linking Moieties
30 Sep 21
The present invention relates to anti-matriptase antibodies and immunoconjugates of anti-matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of matriptase-expressing cancer cells, such as those of multiple myeloma and breast cancers.
Siang-Yo Lin, Joseph R. Bertino, Chen-Yong Lin, Zoltan Szekely
Filed: 12 Mar 21
Utility
Metabolic Biomarkers for Memory Loss
16 Sep 21
The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment.
Howard J. Federoff, Massimo S. Fiandaca, Amrita K. Cheema, Mark E. Mapstone
Filed: 25 Jan 21
Utility
Small molecule androgen receptor inhibitors and methods of use thereof
31 Aug 21
Small molecule carbazole compounds for use as androgen receptor inhibitors are provided herein.
Milton L. Brown, Shujie Hou, Partha Banerjee, Karishma Amin
Filed: 23 Oct 19
Utility
Generating hypotheses in data sets
31 Aug 21
A method for generating hypotheses in a corpus of data comprises selecting a form of ontology; coding the corpus of data based on the form of the ontology; generating ontology space based on coding results and the ontology; transforming the ontology space into a hypothesis space by grouping hypotheses; weighing hypotheses included in the hypothesis space; and applying a science-based optimization algorithm configured to model a science-based treatment of the weighted hypotheses.
Ophir Frieder, David Hartley
Filed: 19 Aug 16
Utility
Method and System for Parametric Speech Synthesis
19 Aug 21
Embodiments of the present systems and methods may provide techniques for synthesizing speech in any voice in any language in any accent.
Joe GARMAN, Ophir FRIEDER
Filed: 14 Jun 19
Utility
ENHANCING CHEMOTHERAPY IN MEDULLOBLASTOMA AND GLIOBLASTOMA WITH HIGH BASAL p53 LEVELS
12 Aug 21
Provided herein is a method of treating medulloblastoma or glioblastoma in a subject by administering to the subject a PI3K activator (e.g., thymosin β-4 or a derivative thereof) and one or more chemotherapeutic agents and/or radiation.
Christopher Albanese, Aisha Naeem
Filed: 12 Mar 19
Utility
Stripline Detector for In Situ Battery and Fuel Cell NMR
5 Aug 21
Provided are batteries and fuel cells incorporating a stripline detector for use in nuclear magnetic resonance (NMR).
YuYe J. TONG, Eric G. SORTE
Filed: 11 Jan 21
Utility
Generating Hypotheses and Recognizing Events In Data Sets
29 Jul 21
A hypotheses generation and event recognition system that enables event recognition by analyzing documents to construct one or more qualitative metrics (e.g., frequency of keywords, changes in sentiment, occurrence of ontological terms, evolution of topics, etc.), establishing a baseline for the qualitative metric(s), and outputting changes to that baseline for display.
David M. Hartley, Nili S. Yossinger, Ophir Frieder
Filed: 31 May 19
Utility
Methods and Compositions for Cell Transplantation
22 Jul 21
Methods of transplanting target cells into a subject in need thereof.
Wanxing Cui
Filed: 2 Aug 19