107 patents
Utility
Compositions and Methods for the Diagnosis and Treatment of Age-related Macular Degeneration
28 Dec 23
The present invention is related to diagnostic, treatment and compound screening methods related to dry age-related macular degeneration (dry AM D).
Nady Golestaneh
Filed: 22 Apr 23
Utility
Compositions and Methods for Enhancing T Cell Penetration of Tumors and Cancers
14 Dec 23
Provided are methods for enhancing anti-tumor and/or anti-cancer immunotherapies.
Allen Cato, Lynda Sutton, Jill P. Smith
Filed: 8 Nov 21
Utility
Specialized Computing Environment for Co-analysis of Proprietary Data
16 Nov 23
A specialized computing environment that includes hardware and data security features to enable competitive organizations to co-analyze proprietary data without revealing the underlying proprietary data to unauthorized users.
David Hartley, Ophir Frieder
Filed: 9 May 23
Utility
Assessing Diseases by Analyzing Gait Measurements
9 Nov 23
A gait analysis system, which includes a neural network with a recurrent neural network layer and a fully connected layer, that receives sensor data indicative of an individual's gait and outputs an assessment regarding the individual's health.
Gholam Motamedi, Ophir Frieder, Cristopher Flagg, Jian-Young Wu
Filed: 26 Jan 23
Utility
Stem Cell-like Memory T Cells and Uses Thereof
12 Oct 23
Provided herein are compositions comprising CD4+ stem cell like memory T (TSCM) cells and their uses in the treatment of cancer, infection and autoimmune disorders.
Samir N. KHLEIF, Vivek VERMA
Filed: 20 Aug 21
Utility
Radiation Mitigator and Method of Use Thereof
5 Oct 23
Milton L. Brown, Yali Kong, Courtney Houchen, Sripathi M. Sureban, Parthasarathy Chandrakesan
Filed: 8 Jun 23
Utility
Wearable Vibrotactile Speech Aid
28 Sep 23
A method for training vibrotactile speech perception in the absence of auditory speech can comprise selecting a first word, generating a first control signal configured to cause at least one vibrotactile transducer to vibrate against a person's body with a first vibration pattern based on the first word, sampling a second word, generating a second control signal configured to cause a vibrotactile transducer to vibrate against the person's body with a second vibration pattern based on the second word, and presenting a comparison between the first word and the second word to the person.
Patrick S. Malone, Maximilian Riesenhuber
Filed: 1 Jun 23
Utility
Combination Therapy of Artemisinin-related Compounds and Histone Deacetylase Inhibitors for Treatment of Hpv-related Benign, Premalignant, and Malignant Diseases
27 Jul 23
Methods of treating human papillomavirus (HPV)-induced conditions, HPV-induced lesions, or HPV-infected cells.
Richard Schlegel, Hang Yuan
Filed: 23 Apr 21
Utility
CADHERIN-11 Inhibitor Formulation and Its Uses In Immunotherapy
6 Jul 23
Provided herein are compositions and methods for the treatment and prevention of cadherin-11 (CDH11) related diseases.
Sivanesan DAKSHANAMURTHY, Ivana PERAN, Stephen W. BYERS, Shahin ASSEFNIA
Filed: 4 Jun 21
Utility
Site- and Structure-specific Core Fucosylation In Liver Disease
6 Jul 23
The instant disclosure provides methods of detecting N-glycopeptides in a sample by contacting the sample with one or more exoglycosidases and detecting the N-glycopeptides by mass spectrometry.
Radoslav GOLDMAN, Miloslav SANDA
Filed: 19 May 22
Utility
Use of Nad+ Precursors, Sting Inhibitors, and FXR Agonists for Inhibiting SARS-COV-2 (COVID-19)-INDUCED Cytokine Release
29 Jun 23
Methods of inhibiting release of one or more cytokines, or inhibiting a cytokine storm, or preventing cytokine release syndrome or a cytokines storm, in a subject infected with severe acquired respiratory syndrome coronavirus 2.
Moshe Levi
Filed: 22 May 21
Utility
Methods of Treating Residual Lesions of Vascular Anomalies
29 Jun 23
Compositions comprising bile acids or their salts and methods of use thereof for the treatment of residual lesions of vascular anomalies.
Cynthia Marie Carver DEKLOTZ, Michael Andrew CARDIS
Filed: 16 Dec 22
Utility
Compositions and Methods for Analyzing Cysteine
25 May 23
The present invention relates to compositions and methods for determining the absolute configuration of D/L-cysteine and/or the enantiomeric composition of cysteine and/or the concentration of total cysteine in a sample.
Christian Wolf, Fathima Yushra Thanzeel
Filed: 26 Nov 22
Utility
Mint Mask and Methods of Use Thereof
4 May 23
Provided are methods and devices useful for treating a respiratory disease or disorder involving the central or upper airways.
Adriane Fugh-Berman
Filed: 30 Sep 22
Utility
Compositions and Methods for Treating Neurodegenerative, Myodegenerative, and Lysosomal Storage Disorders
30 Mar 23
Provided herein are compositions and methods for treating or preventing a neurodegenerative disease, a neurodevelop-mental disease, a myodegenerative disease, a prion disease, a lysosomal storage disease or cancer in a subject.
Charbel MOUSSA, Christian WOLF, Balaraman KALUVU
Filed: 29 Jan 21
Utility
Generating and Testing Hypotheses and Updating a Predictive Model of Pandemic Infections
9 Mar 23
A system that generates and testing hypotheses about the spread of pandemic infections and updates a predictive model of the disease to reflect newly identified hypotheses and/or determinations that previously identified hypotheses are no longer suggested by the latest data.
Ophir Frieder, David Hartley
Filed: 8 Sep 22
Utility
Radiation Mitigator and Method of Use Thereof
2 Feb 23
Milton L. Brown, Yali Kong, Courtney Houchen, Sripathi M. Sureban, Parthasarathy Chandrakesan
Filed: 25 Apr 22
Utility
Apparatus and Methods for Detection and Quantification of Elements In Molecules
26 Jan 23
A method that includes introducing at least one analyte into a gas plasma; generating neutral species from atoms of the analyte in the gas plasma; preferentially transporting the neutral species downstream of the gas plasma relative to any ions produced in the gas plasma; and reacting the neutral species of the analyte with at least one reagent ion downstream of the plasma resulting in ion species of the analyte, wherein the at least one reagent ion is supplied by an independent ion source.
Kaveh Jorabchi, Joseph Lesniewski, Kunyu Zheng, Samuel White
Filed: 25 Feb 21
Utility
Co-Administration Therapy to Prevent Neurodegeneration and Enhance Neuroprotection
22 Dec 22
Described herein are materials and methods for the treatment of neurodegenerative diseases by administering a combination of fenofibrate and kaempferol.
Howard J. Federoff, Sudhakar Raja Subramaniam, Massimo S. Fiandaca, Mark E. Mapstone, Xiaomin Su
Filed: 5 Feb 20
Utility
Large Dzyaloshinskii – Moriya Interaction and Perpendicular Magnetic Anisotropy Induced by Chemisorbed Species on Ferromagnets
22 Dec 22
Embodiments may provide the realization of strong Dzyaloshinskii-Moriya Interaction (DMI) and perpendicular magnetic anisotropy (PMA) induced by chemisorbed species on a ferromagnetic layer.
Gong Chen, Kai Liu, Andreas Schmid
Filed: 13 Aug 20