10 patents
Utility
Method for treating rhabdoid tumors
19 Dec 23
The methods include treating atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene.
Kishor Bhatia, Aditya Kulkarni
Filed: 29 Dec 21
Utility
Illudin Analogs, Uses Thereof, and Methods for Synthesizing the Same
14 Dec 23
This invention provides illudin derivatives, intermediates, preparation methods, pharmaceutical compositions and uses thereof.
Gregory J. Tobin, Shawn T. Blumberg, Andrey D. Malakhov
Filed: 27 Aug 23
Utility
Method for Treating Rhabdoid Tumors
12 Oct 23
The methods include treating atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene.
Kishor Bhatia, Aditya Kulkarni
Filed: 29 Dec 21
Utility
Cancer Drug Sensitivity Determining Markers
28 Sep 23
This application relates to markers for use in the determination of the sensitivity of a cancer patient to an anti-cancer agent (e.g., illudins/illudin analogs) to be administered thereto, which markers can determine whether or not the cancer of the patient has a therapeutic response to the anti-cancer agent, and to application of the markers.
Kishor Bhatia, Aditya Kulkarni
Filed: 18 May 23
Utility
Method for Determining Sensitivity to 2,2'-Dithio-bis-Ethane Sulfonate
13 Jul 23
A method for treating cancer in a patient in which a sample of the tumor or cancer is obtained from the patient and screened for responsiveness to 2,2′-dithio-bis-ethane sulfonate analogs.
Aditya Kulkarni, Kishor Bhatia
Filed: 11 Jul 22
Utility
Increasing Cancer Patient Survival Time by Administration of Dithio-Containing Compounds
6 Jul 23
The present invention discloses and claims compositions, methods of treatment, and kits which cause an increase in the time of survival in cancer patients, wherein the cancer: (i) overexpresses thioredoxin or glutaredoxin and/or (ii) exhibits evidence of thioredoxin- or glutaredoxin-mediated resistance to one or more chemotherapeutic interventions.
Frederick H. Hausheer
Filed: 17 Oct 22
Utility
Increasing cancer patient survival time by administration of dithio-containing compounds
18 Oct 22
The present invention discloses and claims compositions, methods of treatment, and kits which cause an increase in the time of survival in cancer patients, wherein the cancer: (i) overexpresses thioredoxin or glutaredoxin and/or (ii) exhibits evidence of thioredoxin- or glutaredoxin-mediated resistance to one or more chemotherapeutic interventions.
Frederick H. Hausheer
Filed: 31 Mar 15
Utility
Method for Treating Female Non-smokers with Non-small Cell Lung Cancer
2 Jun 22
A method of treating a female patient suffering from non-small cell lung cancer includes the step of administering to the patient in need thereof a composition of 2,2′-dithio-bis-ethane sulfonate, or a pharmaceutically-acceptable salt thereof.
Aditya Kulkarni, Arun Asaithambi
Filed: 8 Sep 21
Utility
Methods for the Treatment of Solid Tumor Cancers Using Illudins and Biomarkers
29 Jul 21
Methods for determining the likelihood that a subject suffering from a solid tumor cancer will benefit from treatment with an illudin are disclosed herein.
Aditya Kulkarni, Yuvanesh Vedaraju, Umesh Kathad, Arun Asaithambi
Filed: 14 Apr 21
Utility
Illudin Analogs, Uses Thereof, and Methods for Synthesizing the Same
1 Jul 21
This invention provides illudin derivatives, intermediates, preparation methods, pharmaceutical compositions and uses thereof.
Gregory J. Tobin, Shawn T. Blumberg, Andrey D. Malakhov, Varsin A. Archer
Filed: 4 Mar 21
- Prev
- 1
- Next
Patents are sorted by USPTO publication date, most recent first