14 patents
Utility
Combination Therapy of MDNA55 and a Vascular Endothelial Growth Factor a (Vegf-a)
21 Dec 23
Methods for treating a central nervous system (CNS) tumor in a subject, comprising administering to the subject MD-NA55 in combination with a vascular endothelial growth factor A (VEGF-A) inhibitor administered at a subtherapeutic level.
Fahar Merchant
Filed: 12 Oct 21
Utility
Bifunctional Superkines and Uses Thereof
16 Nov 23
Bispecific human interleukin-2 (IL-2) cytokine fusions are provided.
Fahar Merchant
Filed: 24 Jun 21
Utility
IL-2 Superagonists In Combination with ANTI-PD-1 Antibodies
16 Mar 23
Human interleukin-2 (IL-2) muteins or variants thereof are provided.
Fahar Merchant, Shafique Fidai
Filed: 2 Aug 22
Utility
IL-2 superagonists in combination with anti-PD-1 antibodies
3 Jan 23
Human interleukin-2 (IL-2) muteins or variants thereof are provided.
Fahar Merchant, Shafique Fidai
Filed: 19 Jun 18
Utility
Interleukin-4 Receptor-Binding Fusion Proteins and Uses Thereof
24 Nov 22
The present invention relates to interleukin-4 receptor-binding fusion proteins.
Fahar Merchant, Raj K. Puri, Joshi H. Bharatkumar
Filed: 6 May 22
Utility
IL-4R As a Biomarker In Cancer
3 Nov 22
Methods for using the human interleukin-4 receptor (IL-4) as a biomarker for determining patent populations for treatment, predicting disease treatment efficacy, and predicting disease treatment prognosis in a variety of cancers, in particular glioblastoma and recurrent glioblastoma.
Fahar Merchant, Rosemina Merchant
Filed: 7 Feb 20
Utility
Interleukin-4 receptor-binding fusion proteins and uses thereof
7 Jun 22
The present invention relates to interleukin-4 receptor-binding fusion proteins.
Fahar Merchant, Raj K. Puri, Bharatkumar H. Joshi
Filed: 7 Sep 18
Utility
INTERLEUKIN-4 Receptor-binding Fusion Proteins and Uses Thereof
17 Feb 22
The present invention relates to interleukin-4 receptor binding fusion proteins.
Fahar Merchant, Raj K. Puri, Bharatkumar H. Joshi
Filed: 9 Aug 21
Utility
INTERLEUKIN-2 Fusion Proteins and Uses Thereof
12 Aug 21
The present invention relates to interleukin-2 fusion proteins.
Fahar Merchant
Filed: 12 Aug 20
Utility
Interleukin-4 receptor-binding fusion proteins and uses thereof
10 Aug 21
The present invention relates to interleukin-4 receptor binding fusion proteins.
Fahar Merchant, Raj K. Puri, Bharatkumar H. Joshi
Filed: 7 Sep 18
Utility
Uses and Methods for Oncolytic Virus Targeting of IL-4/IL-13 and Fusions Thereof
5 Aug 21
The present invention provides an oncolytic virus vector containing a sequence encoding IL-4 receptor targeted cargo protein, including IL-4 muteins and/or IL-13 muteins, the oncolytic virus encoded therefrom, the uses of the oncolytic virus for treating cancer.
Fahar Merchant
Filed: 3 Jun 19
Utility
IL-13/IL-4 Superkines: Immune Cell Targeting Constructs and Methods of Use Thereof
15 Jul 21
Methods and compositions are provided for enhancing anti-tumor effector immune cells with a targeting construct comprising a human IL-13 superkine and/or a human IL-4 superkine.
Kenan Christopher Garcia, Ignacio Moraga Gonzalez, Fahar Merchant
Filed: 3 Jun 19
Utility
IL-4-FUSION Formulations for Treatment of Central Nervous System (CNS) Tumors
16 Dec 20
The present invention provides methods for the treatment of a central nervous system (CNS) tumor in a subject comprising administering and IL-4 targeted cargo protein formulated in an artificial cerebral spinal fluid formulation.
Fahar Merchant
Filed: 9 Oct 18
Utility
Interleukin-2 fusion proteins and uses thereof
21 Sep 20
The present invention relates to interleukin-2 fusion proteins.
Fahar Merchant
Filed: 23 Sep 14
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