7 patents
Utility
FGFR inhibitors and methods of use thereof
10 Oct 23
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of FGFR enzymes with the compounds and compositions of the disclosure.
Bakary-Barry Touré, Heike Schoenherr, Fabrizio Giordanetto, Demetri T. Moustakas, Brandi M. Hudson
Filed: 31 Jan 23
Utility
Pyrazolo[3,4-b]pyrazine derivatives as SHP2 phosphatase inhibitors
18 Jul 23
Cellular biological activities are tightly controlled by intracellular signaling processes initiated by extracellular signals.
Alexander M. Taylor, W. Patrick Walters, Mark Andrew Murcko, Fabrizio Giordanetto, Eric Therrien, Sathesh Bhat, Markus Kristofer Dahlgren
Filed: 28 Sep 18
Utility
SHP2 phosphatase inhibitors and methods of use thereof
18 Apr 23
The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the invention.
Fabrizio Giordanetto, Jack Benjamin Greisman, Paul Maragakis, Alexander M. Taylor, Lucian V. Dipietro, Elizabeth H. Kelley, André Lescarbeau, Mark Andrew Murcko, Levi Charles Thomas Pierce, Kelley C. Shortsleeves, W. Patrick Walters, Sathesh Bhat, Eric Therrien, Markus Kristofer Dahlgren
Filed: 24 Oct 17
Utility
Substituted pyrazolo[3,4-b]pyrazines as SHP2 phosphatase inhibitors
28 Feb 23
Alexander M. Taylor, André Lescarbeau, Elizabeth H. Kelley, Kelley C. Shortsleeves, Lucian V. DiPietro, W. Patrick Walters, Mark Andrew Murcko, Levi Charles Thomas Pierce, Yong Tang, Fabrizio Giordanetto, Jack Benjamin Greisman, Paul Maragakis, Sathesh Bhat, Markus Kristofer Dahlgren, Eric Therrien
Filed: 25 May 18
Utility
SHP2 phosphatase inhibitors and methods of use thereof
20 Dec 22
Brian K. Albrecht, Fabrizio Giordanetto, Jack Benjamin Greisman, Paul Maragakis, Alexander M. Taylor, W. Patrick Walters
Filed: 22 Sep 17
Utility
Pyrazolo[3,4-b]pyrazine derivatives as SHP2 phosphatase inhibitors
20 Dec 22
Cellular biological activities are tightly controlled by intracellular signaling processes initiated by extracellular signals.
Alexander M. Taylor, W. Patrick Walters, Mark Andrew Murcko, Fabrizio Giordanetto, Eric Therrien, Sathesh Bhat, Markus Kristofer Dahlgren
Filed: 28 Sep 18
Utility
SHP2 phosphatase inhibitors and methods of use thereof
2 Mar 21
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure.
Alexander M. Taylor, André Lescarbeau, Elizabeth H. Kelley, Kelley C. Shortsleeves, W. Patrick Walters, Mark Andrew Murcko, Fabrizio Giordanetto, Eric Therrien
Filed: 28 May 20
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