1604 patents
Page 9 of 81
Utility
Applications of engineered
11 Jul 23
Engineered Streptococcus canis Cas9 (ScCas9) variants include an ScCas9 protein with its PID being the PID amino acid composition of Streptococcus pyogenes Cas9 (SpCas9)-NG, an ScCas9 protein having a threonine-to-lysine substitution mutation at position 1227 in its amino acid sequence (Sc+), and an ScCas9 protein having a threonine-to-lysine substitution mutation at position 1227 and a substitution of residues ADKKLRKRSGKLATE [SEQ ID No. 4] in position 365-379 in the ScCas9 open reading frame (Sc++).
Pranam Chatterjee, Noah Michael Jakimo, Joseph M. Jacobson
Filed: 30 Jun 22
Utility
Multiplexed sensor network using swept source Raman spectroscopy
11 Jul 23
Swept-source Raman spectroscopy uses a tunable laser and a fixed-wavelength detector instead of a spectrometer or interferometer to perform Raman spectroscopy with the throughput advantage of Fourier transform Raman spectroscopy without bulky optics or moving mirrors.
Rajeev J. Ram, Amir H. Atabaki, Nili Persits, Jaehwan Kim
Filed: 1 Jun 21
Utility
Systems, devices, and methods for rheological measurement of yield stress fluids using fractal-like fixtures
11 Jul 23
The present disclosure is directed to rheometric fixtures for making rheological measurements of yield stress fluids.
Crystal Elaine Owens, Gareth H. McKinley, Anastasios John Hart
Filed: 15 Oct 20
Utility
Near infrared fluorescent biosensors for steroid hormones
11 Jul 23
Corona Phase Molecular Recognition (CoPhMoRe) utilizing a template heteropolymer adsorbed onto and templated by a nanoparticle surface to recognize a specific target analyte can be used for macromolecular analytes, including proteins.
Michael Strano, Michael Lee, Naveed Bakh, Song Wang
Filed: 4 May 20
Utility
All-to-all connected oscillator networks for solving combinatorial optimization problems
11 Jul 23
An analog computing system with coupled non-linear oscillators can solve complex combinatorial optimization problems using the weighted Ising model.
Jeffrey Chou, Suraj Deepak Bramhavar, Siddhartha Ghosh, William Herzog
Filed: 27 Mar 20
Utility
Qubit circuits with deep, in-substrate components
11 Jul 23
Qubit circuits having components formed deep in a substrate are described.
Wayne Woods, Danna Rosenberg, Cyrus Hirjibehedin, Donna-Ruth Yost, Justin Mallek, Andrew Kerman, Mollie Schwartz, Jonilyn Yoder, William Oliver, Thomas Hazard
Filed: 4 Jan 21
Utility
Bilayer component for a lithium battery
11 Jul 23
A component for a lithium battery including a first layer including a lithium garnet having a porosity of 0 percent to less than 25 percent, based on a total volume of the first layer; and a second layer on the first layer and having a porosity of 25 percent to 80 percent, based on a total volume of the second layer, wherein the second layer is on the first layer and the second layer has a composition that is different from a composition of the first layer.
Won Seok Chang, Zachary Hood, Jennifer Rupp, Lincoln Miara
Filed: 8 Dec 20
Utility
Methods and system for multi-channel bio-optical sensing
4 Jul 23
A sensor, such as a photoplethysmography sensor, for non-invasively monitoring a characteristic of an organism, such as a vital body sign.
Juejun Hu, Tian Gu
Filed: 13 Feb 18
Utility
Variable compression body anchor
4 Jul 23
In some embodiments, a body anchor for supporting an assistive device can include: a cuff to exert a compression force on a body part of a user; and one or more tensile elements having first ends and second ends.
Meghan Huber, James Hermus, Gabrielle Enns, Neville Hogan
Filed: 13 Feb 20
Utility
Material joining using jet locking
4 Jul 23
Joining methods and corresponding structures are disclosed.
David Veysset
Filed: 27 Aug 20
Utility
Robot control at singular configurations
4 Jul 23
According to some embodiments, a method includes: receiving an endpoint impedance matrix representing a desired stiffness or damping at the robot endpoint; reflecting the endpoint impedance matrix to an equivalent joint-space matrix associated with one or more of the robot joints, the equivalent joint-space matrix having a nullspace corresponding to near-zero-valued eigenvalues; generating a nullspace-filled impedance matrix from the equivalent joint-space matrix based in part on replacing the near-zero-valued eigenvalues with selected finite positive real values; generating a robot control law using the nullspace-filled impedance matrix; and using the robot control law to control the robot.
David Verdi, Neville Hogan
Filed: 3 Nov 20
Utility
Portable spectrometer for chemical sensing
4 Jul 23
Techniques are disclosed for a chemical sensor architecture based on a fabric-based spectrometer.
Richard Kingsborough, Alexander Stolyarov, Shane Tysk, Lauren Cantley
Filed: 21 Aug 20
Utility
Potassium-releasing material
4 Jul 23
The present disclosure, in various embodiments, discloses hydrothermal methods, hydrothermally modified materials and dried hydrothermally modified materials.
Davide Ciceri, Marcelo De Oliveira, Antoine Allanore, Dennis P. Chen, Thomas C. Close
Filed: 1 Oct 20
Utility
Near-to-eye and see-through holographic displays
4 Jul 23
A holographic display is comprised of space-multiplexed elemental modulators, each of which consists of a surface acoustic wave transducer atop an anisotropic waveguide.
Sundeep Jolly, Nickolaos Savidis, V. Michael Bove, Jr., Bianca Datta, Daniel E. Smalley
Filed: 31 Jul 20
Utility
Magnetic transmission
4 Jul 23
Magnetic transmissions and related methods are described.
Martin Culpepper, Marcel Thomas
Filed: 30 Nov 20
Utility
Active noise cancelation in superconducting Qubits using closed-loop feedback
4 Jul 23
A closed-loop feedback system and method of active noise cancellation to maintain a desired operating frequency of a qubit during a quantum computation, even when that frequency is relatively sensitive to flux noise.
Roni Winik, Antti Pekka Vepsalainen, Simon Gustavsson, William D. Oliver
Filed: 25 Feb 22
Utility
Gastric resident electronics
27 Jun 23
Gastric resident electronics, devices, systems, and related methods are generally provided.
Robert S. Langer, Carlo Giovanni Traverso, Yong Lin Kong
Filed: 28 Nov 18
Utility
Compositions and related methods for targeted drug delivery
27 Jun 23
Compositions, articles, and methods for targeted drug delivery, such as thermoresponsive hydrogel polymers, are generally provided.
Carlo Giovanni Traverso, Ashok Kakkar, Joshua Korzenik, Robert S. Langer, Sufeng Zhang
Filed: 8 Dec 17
Utility
Medical devices and implements with liquid-impregnated surfaces
27 Jun 23
Described herein are medical devices and medical implements with high lubricity to flesh (or biological fluid) and/or inhibited nucleation on its surface.
J. David Smith, Rajeev Dhiman, Adam T. Paxson, Christopher J. Love, Brian R. Solomon, Kripa K. Varanasi
Filed: 9 Jun 21
Utility
Wireless non-radiative energy transfer
27 Jun 23
Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, a second high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator.
John D. Joannopoulos, Aristeidis Karalis, Marin Soljacic
Filed: 31 Aug 21