14 patents
Utility
Nucleic acids encoding antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
2 Jan 24
The invention relates to antibodies that are capable of specifically binding TREM-1 and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages and neutrophils.
Vibeke Westphal Stennicke, Christine Brender Read, Susanne Nedergaard Grell, Charlotte Wiberg, Rune Salbo, Anette Henriksen, Soeren Padkjaer
Filed: 1 Feb 21
Utility
ApoC-II mimetic peptides
28 Nov 23
The disclosure provides apolipoprotein C-II (apoC-II) mimetic peptides and methods for treating hypertriglyceridemia in a patient with an effective amount of an apoC-II mimetic peptide.
Alan Thomas Remaley, Soumitra Shanker Ghosh, Madhav N. Devalaraja, Chih-Hung Lo, Denis O. Sviridov, Anna Wolska
Filed: 9 Mar 21
Utility
Drug delivery device with information capture
30 Nov 20
A drug delivery device is provided comprising or adapted to receive a cartridge with an axially displaceable piston.
Andre Larsen, Henrik Riehm Soerensen
Filed: 8 Nov 16
Utility
Stable multi-dose compositions comprising an antibody and a preservative
16 Nov 20
The invention relates to stable, multi-dose liquid compositions containing proteins, in particular, but not exclusively stable antibodies, and to the use of said compositions in therapy, in particular for the subcutaneous delivery of said stable protein.
Henrik Parshad, Dorthe Kot Engelund
Filed: 30 Oct 17
Utility
Drug delivery system with multipolar magnet and sensor system
16 Nov 20
A drug delivery system comprises an indicator element and a sensor system.
Nikolaj Eusebius Jakobsen, Preben Mikael Nielsen, Nikolaj Frogner Krusell, Laurits Hoejgaard Olesen
Filed: 14 Jun 20
Utility
Shielded needle cannula
9 Nov 20
The invention relates to an injection system or a needle assembly in which a needle cannula secured to an injection device is shielded by a axially movable needle shield.
Bjoern Gullak Larsen, Christoffer Busk Stormoen, Kurt Solgaard, Thomas Olund Christensen
Filed: 10 Nov 16
Utility
EGF(A) analogues with fatty acid substituents
2 Nov 20
The invention relates to compounds derived from the EGF(A) domain of LDL-R, in particular compounds comprising a peptide analogue of the wild-type EGF(A) (LDL-R(293-332)) sequence and at least one substituent comprising at least one fatty acid group.
Jianhe Chen, Jesper F. Lau, Janos Tibor Kodra, Birgit Wieczorek, Lars Linderoth, Henning Thoegersen, Salka Elboel Rasmussen, Patrick William Garibay
Filed: 12 Jan 17
Utility
Drug delivery device with information capture
26 Oct 20
A drug delivery device is provided comprising or adapted to receive a cartridge with an axially displaceable piston.
Andre Larsen, Henrik Riehm Soerensen
Filed: 8 Nov 16
Utility
Anti-KIR antibodies, formulations, and uses thereof
26 Oct 20
A novel IgG4 isotype anti-KIR antibody, novel formulations of this and other IgG4 anti-KIR antibodies, and methods of using such formulations are provided.
Peter Andreas Nicolai Reumert Wagtmann, Ivan Svendsen, Rozana Sten, Lene Hjorth Alifrangis, Rune Viig Overgaard
Filed: 19 Dec 17
Utility
Pressure based event detection
19 Oct 20
The present invention provides a drug delivery device (1) comprising a drug delivery unit (10) comprising a dose expelling mechanism operable to expel a dose of drug from a drug reservoir (11), a cap (20) configured for dismountable mounting over a portion of the drug delivery unit (10), the cap (20) comprising a cavity (25, 26) for reception of the portion of the drug delivery unit (10), a seal (40) adapted to provide a sealing in an interface between the cap (20) and the drug delivery unit (10), a sensor system (30) configured to monitor internal pressure in the cavity (25, 26) and to register an event in response to sensing a change in the internal pressure which numerically exceeds a specified threshold level over a period of less than 5 seconds, and energy means (50) for powering the sensor system (30).
Ulrik Detlef Raedisch Poulsen
Filed: 30 Jun 16
Utility
Method of manufacturing one of a range of autoinjectors
12 Oct 20
A method of manufacturing one of a range of autoinjectors having cartridges (600, 600′, 600″) with different preset fill volumes, the method comprising the steps of: a) providing a front body assembly (100b, 100c, 100c′, 100c″), b) providing a cartridge (600, 600′, 600″) of given fill volume, c) providing a rear body assembly (100a) comprising a spring-driven drive ram assembly (310, 320) configured to drive the piston of a held cartridge (600, 600′, 600″), d) providing a ram spacer member (400, 400′, 400″), the ram spacer member defining a spacing geometry of length dimension (X1′, X1″, X1′″, XS′, XS″, XS′″, XR′, XR″, XR′″) selected according to the fill volume of the cartridge (600, 600′, 600″), and e) assembling a front body assembly (100b, 100c, 100c′, 100c″), the cartridge (600, 600′, 600″), the ram spacer member (400, 400′, 400″) and the rear body assembly (100a) so that the ram spacer member (400, 400′, 400″) is arranged axially between the drive ram assembly (310, 320) of the rear body assembly (100a) and the piston of a held cartridge (600, 600′, 600″).
Mads Schenstroem Stefansen, Soeren Kjellerup Hansen, Klaus Bendix
Filed: 11 Nov 15
Utility
Method for moulding a polymeric housing for a medical injection device
12 Oct 20
The invention relates to a medical injection device having a polymeric housing or housing parts.
Ken Hansen, Imran Ghulam, Jesper Bach Noergaard, Claus Urup Gjoedesen, Asger Meng Larsen
Filed: 26 May 16
Utility
Deformable piston washer
28 Sep 20
The present invention provides a piston washer (1, 51) for a drug delivery device, the piston washer (1, 51) comprising a central portion (2, 72) arranged about a centre axis, a peripheral portion (3, 73), and an axially pliable structure (8, 78) connecting the central portion (2, 72) and the peripheral portion (3, 73).
Nikolaj Eusebius Jacobsen
Filed: 3 Mar 16
Utility
Medical injection device with needle cleaning
14 Sep 20
The invention relates to a prefilled injection pen for apportioning multiple set doses of a liquid drug.
Simon Munch Pedersen, Lars Eilertsen, Morten Revsgaard Frederiksen, Ruben Archilla, Mattias Ingerslev, Bo Radmer, Rasmus Kann Jensen, Kurt Solgaard
Filed: 19 Jun 17
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