86 patents
Utility
Circular economic methods for fragrance ingredients
16 Jan 24
Disclosed is a method for converting cymene generated from renewable low value terpene streams into renewable benzene, toluene, xylenes, and cymene isomers (ortho and meta) under flow disproportionation reaction conditions, which compounds are basic building blocks for fragrance materials.
Sunitha R. Tadepalli, Paul Daniel Jones, Geatesh K. Tampy, John P. Cherkauskas
Filed: 27 Jul 20
Utility
Compositions and methods for increased protein production in bacillus licheniformis
9 Jan 24
The present disclosure is generally related to compositions and methods for obtaining Bacillus licheniformis cells/strains having increased protein production capabilities.
Marc Anton Bernhard Kolkman, Steven D. Doig, Ryan L. Frisch, Hongxian He, Frank Wouter Koopman, Chris Leeflang
Filed: 22 Feb 18
Utility
Compositions and methods comprising the use of a
2 Jan 24
Bacillus agaradhaerens strain WDG185 expresses an inulosucrase that efficiently synthesizes a broad range of IOS with a GF range of GF3-GF30.
Slavko Kralj, Marc Kolkman, Chris Leeflang, Johannes G. De Nobel, Arjen Hoekstra, Veli Alkan
Filed: 17 Sep 20
Utility
Enzymatic modification of wheat phospholipids in bakery applications
19 Dec 23
The present invention relates to a method of making a dough, said method comprises admixing a dough component, a phospholipase A2 enzyme which acts on N-acyl phosphatidyl ethanolamine at the sn2 position, and an enzyme that acts on a polar lipid at the sn1 position.
Jorn Borch Soe, Rene Mikkelsen, Tina Lillan Joergensen
Filed: 28 Apr 21
Utility
Alpha-glucose-1-phosphate synthesis from sucrose and glucan synthesis using glucan phosphorylases
31 Oct 23
Reactions are disclosed herein comprising water, alpha-glucose-1-phosphate (alpha-G1P), an acceptor molecule, and an alpha-1,4-glucan phosphorylase.
Slavko Kralj, Zheyong Yu, Zhenghong Zhang
Filed: 18 Jul 19
Utility
Promoter sequences and methods thereof for enhanced protein production in
10 Oct 23
The present disclosure is generally related to novel promoter sequences and methods thereof for enhanced protein production in Bacillus sp. (host) cells.
Stacey Irene Robida Stubbs, Cristina Bongiorni, Ryan L. Frisch, Chris Leeflang
Filed: 25 Nov 19
Utility
Cas9 variants and methods of use
10 Oct 23
Compositions and methods are provided for variant Cas systems and elements comprising such systems, including, but not limiting to, Cas endonuclease variants, guide polynucleotide/Cas endonuclease complexes comprising Cas endonuclease variants, as well as guide polynucleotides and guide RNA elements that can interact with Cas endonuclease variants.
Ryan L. Frisch, Hongxian He
Filed: 11 Dec 18
Utility
Methods of using cosmetic compositions comprising exopolysaccharides derived from microbial mats
12 Sep 23
A skin care composition is disclosed comprising at least one exopolysaccharide (EPS) originating from a microbial mat, the EPS being in a concentration of about 0.001% w/w to about 1.5% w/w of the composition.
Estelle Loing, Sandrine Briatte, Patrice Dionne, Martin Beaulieu, Xavier Moppert, Laurent Richert, Catherine Vayssier
Filed: 12 May 21
Utility
Circular economy methods of preparing unsaturated compounds
12 Sep 23
Methods of preparing unsaturated compounds or analogs through dehydrogenation of corresponding saturated compounds and/or hydrogenation of aromatic compounds are disclosed.
Sunitha Rao Tadepalli, Geatesh Karunakaran Tampy, Anubhav P. S. Narula
Filed: 30 Aug 19
Utility
Synthesis of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene
12 Sep 23
Disclosed is a scalable process for preparation of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene (BCE), a key intermediate for manufacture of fragrance ingredient 3-methylcyclopentadecenone (MUSCENONE®) and analogs through reaction of 3-Methyl-1,5-cyclopentadecanedione (MCPD) and analogs with a metal or metalloid alkoxide in high yield and purity.
Mohamad Gara, Yigal Becker
Filed: 16 Jan 20
Utility
Enzymatic modification of phospholipids in food
5 Sep 23
A phospholipase A1 characterized by having an sn1/sn2 specificity ratio of about 55/45 or greater wherein said phospholipase A1 has a lysophospholipase/phospholipase activity ratio of less than 0.02 is presented in conjunction with methods for use in lipid containing food matrix, baking and making dough with the phospholipase and also including baking improvers using the disclosed phospholipase A1.
Keya Zhang, Lone Broend Miller, Lene Kragh, Tina Lillan Joergensen
Filed: 17 Dec 18
Utility
Anti-CRISPR polynucleotides and polypeptides and methods of use
22 Aug 23
Methods and compositions are provided for the use of anti-CRISPR (ACR) proteins in plants, including modulation of Cas endonuclease activity, improvement of frequency of homologous recombination, control of Cas endonuclease activity during various cell cycles, spatial and/or temporal regulation of Cas endonuclease activity in plants, usage in gene activation or repression, as well as reduction of off-target polynucleotide cleavage.
Christophe Fremaux, Philippe Horvath, Alexander Hynes, Marie-Laurence Lemay, Sylvain Moineau, Dennis A. Romero, Geneviève Rousseau, Joshua K Young
Filed: 24 Apr 18
Utility
Lactic acid bacteria with sweetening properties and uses thereof
15 Aug 23
The invention is directed to a lactose-positive, galactose-negative, Streptococcus thermophilus strain releasing glucose during milk fermentation.
Armelle Cochu-Blachere, Christophe Fremaux, Thomas Desfougeres
Filed: 21 Dec 18
Utility
Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-CoA-derived products
27 Jun 23
The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, isoprenoids, and/or acetyl-CoA-derived products in recombinant microorganisms by engineering the microorganisms to comprise one or more acetylating proteins such that the expression and/or activity of the one or more acetylating proteins is modulated.
Marguerite A. Cervin, Michael C. Miller, Derek H. Wells, Alan J. Wolfe, Madhukar S. Dasika
Filed: 11 May 20
Utility
Protease variants and uses thereof
30 May 23
Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
David Marquez, Michael Stoner, James T. Kellis, Jr., Adam Garske, Joshua Roy Basler, Katherine Augustyn, Priyanka Chandrasekaran, Miles Christopher Scotcher, Lilia Maria Babe, Richard R. Bott, David A. Estell, Gudrun Vogtentanz, Sina Pricelius, Jian Yao
Filed: 31 May 17
Utility
Production of brewer's wort having increase fermentable sugars for fermentation
25 Apr 23
The present disclosure provides methods, compositions, apparatuses and kits comprising two or more distant related glucoamylases in mashing having a synergistic effect on the released fermentable DPI sugar.
Jacob Flyvholm Cramer, Tove Bladt
Filed: 19 Sep 18
Utility
Colloidal stabilizer effective at low concentrations
14 Mar 23
This invention relates to making and using a stabilizer that is effective in small amounts and, particularly useful for stabilizing low solids liquids, e.g., dispersions, emulsions, and suspensions, used in foods, pharmaceuticals, nutraceuticals, and similar industrial applications, which comprises, microcrystalline cellulose, (preferably, colloidal hydrolyzed MCC); a first carboxymethyl cellulose having a viscosity of 30-85 cP at 2% in deionized water; and, a degree of carboxymethyl substitutions of 0.60 to 0.85, and a second carboxymethyl cellulose having a viscosity of 400-800 cP at 2% in deionized water, and a degree of carboxymethyl substitutions of 0.80 to 0.95; and, the stabilizer may be made by preparing a moist MCC “wetcake”; thoroughly mixing the wetcake with a dry blended mixture of low DS and medium DS, CMCs; preferably, in a MCC/low DS CMC/medium DS CMC ratio range of about 88/6/6 to about 92/4/4, adding that mixture to an extruder; preparing a slurry of the extrudate in deionized water; and, optionally, pumping the slurry to a spray dryer to produce a powder.
Zheng Tan, Mei Yan Joyce Toh, Simon Patrick Charles Eustace, Jeremy Ondov
Filed: 11 Aug 17
Utility
Compositions containing microcapsules coated with deposition proteins
14 Mar 23
A microcapsule composition containing microcapsules is provided as is a method for making the microcapsule composition and using the microcapsule composition in consumer products.
Takashi Sasaki, Johan G. L. Pluyter
Filed: 27 Aug 21
Utility
Synergistic combination of 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione with glyoxal
28 Feb 23
A synergistic antimicrobial composition having two components.
Nora Eibergen, Geert van der Kraan
Filed: 20 Mar 19
Utility
Compositions and methods for remediation of sulfate reducing prokaryotes
21 Feb 23
Compositions and methods are provided for use in controlling souring and corrosion causing prokaryotes, such as SRP, by treating oil and gas field environments or treatment fluids with a newly identified bacterial strain ATCC Accession No.
Kathleen Manna, Ian A. Tomlinson, Abhiram Thatipelli, Christopher Janes, Elizabeth J. Summer
Filed: 6 Jul 18