39 patents
Page 2 of 2
Utility
Fast Startup Ion Chromatography System and Methods
16 Dec 21
Systems and methods for inhibiting translocation of ions across ion exchange barriers include an eluent generator having an ion source reservoir with a first electrode, an eluent generation chamber with a second electrode, an ion exchange barrier disposed therebetween, and means for reversing the polarity of a voltage or current applied across the first and second electrodes.
Kannan Srinivasan, Mrinal Sengupta, Yan Liu, Christopher A. Pohl, Nebojsa Avdalovic
Filed: 27 Aug 21
Utility
Replaceable Emitter Assembly for Interfacing a Separation Column to a Mass Spectrometer
18 Nov 21
An electrospray emitter assembly for interfacing a separation column to a mass spectrometer is disclosed.
Brandon Howard ROBSON, Xuefei SUN, Xiaodong LIU
Filed: 24 May 21
Utility
Sulfonamide Based Anion Exchange Resins
7 Oct 21
An ion exchange resin for use as a stationary phase in an ion chromatography column.
Melvin Hatch, Christopher A. Pohl, Manikandan Jayaraman
Filed: 22 Jun 21
Utility
Chromatographic Material Having Improved PH Stability, Method for Preparation Thereof and Uses Thereof
15 Jul 21
A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group.
Xiaodong LIU, Xiao CUI, Xuefei SUN
Filed: 11 Jan 21
Utility
Electrolytic Eluent Generators with Stabilized Operating Voltages
17 Jun 21
An electrolytic eluent generator includes an electrolyte reservoir, an eluent generation chamber, and an ion exchange membrane stack.
Zhongqing LU, Yan LIU, Christopher A. POHL, Jinhua CHEN, Jun CHENG
Filed: 16 Dec 19
Utility
Anion Exchange Stationary Phases Based on a Polyalkylpolyamine Polymer Layer
3 Jun 21
An anion exchange for separating a plurality of carbohydrates includes a negatively charged substrate particle.
Christopher A. Pohl, Jinhua Chen
Filed: 15 Feb 21
Utility
Vial Cap and Method for Removing Matrix Components from a Liquid Sample
3 Jun 21
A vial cap for removing a matrix component from a liquid sample is described.
Christopher A. POHL, Rosanne W. SLINGSBY
Filed: 12 Feb 21
Utility
Longitudinal Gradient Chromatography Columns
6 May 21
An ion exchange chromatography column contains an ion exchange stationary phase that includes a charged substrate, a plurality of first particles, and a plurality of second particles.
Christopher A. Pohl
Filed: 4 Nov 19
Utility
Functionalized Polyolefin Capillaries for Open Tubular Ion Chromatography
21 Jan 21
Open tubular capillary columns for liquid and ion chromatography, based upon an ionically impermeable polyolefin capillary having a bore with a sulfonate-group- or amine-group-functionalized internal surface.
Purnendu K. DASGUPTA, Weixiong HUANG, Christopher A. POHL
Filed: 16 Sep 20
Utility
Methods and Systems for Optimizing Buffer Conditions with Liquid Chromatography
9 Dec 20
A plurality of chromatograms is run using a salt gradient with a range of constant pH values or using a pH gradient with a range of constant salt concentrations.
Shanhua Lin Liehr, Jung Un Baek, Christopher A. Pohl, Mark Lee Tracy, Xiadong Liu
Filed: 8 Jun 19
Utility
Replaceable Emitter Assembly for Interfacing a Separation Column to a Mass Spectrometer
18 Nov 20
An electrospray emitter assembly for interfacing a separation column to a mass spectrometer is disclosed.
Brandon Howard ROBSON, Xuefei SUN, Xiaodong LIU
Filed: 19 Apr 20
Utility
Hydrophilic Anion Exchange Chromatography Media
30 Sep 20
An anion exchange stationary phase comprises substrate particles, a based condensation polymer layer attached to the substrate particles, one or more alkylamine condensation polymer layers covalently attached to base condensation polymer layer, and a terminating condensation layer covalently attached to the alkylamine condensation polymer layer.
Christopher A. Pohl, Manikandan JAYARAMAN
Filed: 28 Mar 19
Utility
Ion Exchange Chromatography Column, Method, and System Thereof
19 Aug 20
An ion exchange chromatographic packing material is described that includes support resin particles and a copolymer grafted to the support resin particles.
Manikandan JAYARAMAN, Christopher A. POHL, Charanjit SAINI
Filed: 3 May 20
Utility
Suppressors with Eluent Screens for Use In Ion Chromatography
29 Jul 20
A suppressor for use in reducing a background signal while detecting analytes in a liquid sample for ion chromatography is described.
Kannan SRINIVASAN, Sheetal BHARDWAJ, Glenn M. KUSE
Filed: 24 Jan 19
Utility
Vial Cap and Method for Removing Matrix Components from a Liquid Sample
4 Mar 20
A vial cap for removing a matrix component from a liquid sample is described.
Christopher A. POHL, Rosanne W. SLINGSBY
Filed: 6 Nov 19
Utility
Anion Exchange Stationary Phases Based on Crosslinked Hydroxyalkylamine Layer and Glycidol
12 Feb 20
An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer.
Charanjit SAINI, Christopher A. POHL
Filed: 9 Aug 18
Utility
Anion Exchange Stationary Phases Based on a Polyalkylpolyamine Polymer Layer
29 Jan 20
An anion exchange for separating a plurality of carbohydrates includes a negatively charged substrate particle.
Christopher A. POHL, Jinhua CHEN
Filed: 29 Jul 18
Utility
Multimodal Chromatographic Media for Protein Separation
27 Nov 19
A chromatographic media for separating bio-polymers, the chromatographic media having cationic exchange properties and anionic exchange properties, the chromatographic media comprising: (a) non-porous substrate particles including an organic polymer, the substrate particles having a neutral hydrophilic layer at a surface of the non-porous substrate particles, in which the neutral hydrophilic layer is configured to reduce a binding of the bio-polymers directly to the non-porous substrate particles compared to a binding of the bio-polymer to the non-porous substrate particles without the neutral hydrophilic layer; (b) a charged first ion exchange layer bound to the substrate particles on top of the hydrophilic layer, the first ion exchange layer comprising first ion exchange groups; and (c) a charged second ion exchange layer bound to the substrate particles on top of the first ion exchange layer.
Christopher A. Pohl, Xiaodong Liu, Shanhua Lin Liehr
Filed: 17 Jan 18
Utility
Ion Exchange Based Volatile Component Removal Device for Ion Chromatography
23 Oct 19
A method, device, and system for removing a volatile component from a liquid solution for a chromatographic separation are described.
Kannan SRINIVASAN, Sheetal BHARDWAJ
Filed: 25 Apr 19