93 patents
Utility
Alternating Tangential Flow Bioreactor with Hollow Fiber System and Method of Use
19 Jan 23
Embodiments of the present disclosure relate generally to systems and methods for perfusion cell culture involving alternating fluid flows between first and second flexible vessels.
Bao Le, Travis R. Ward
Filed: 14 Dec 20
Utility
Method for proliferation of cells within a bioreactor using a disposable pumphead and filter assembly
17 Jan 23
A method for promoting biological activity uses a filter system to increase cell production of a fed batch bioreactor.
David Serway
Filed: 31 May 22
Utility
Fc binding proteins with cysteine in the c-terminal helical region
10 Jan 23
The present invention relates to Fc binding proteins comprising one or more domains with Cysteine in the C-terminal helical region.
Erik Fiedler, Ulrich Haupts
Filed: 28 Jan 19
Utility
Offline and Inline Determination of Concentration of Metabolites In Cell Culture Fluid
5 Jan 23
Devices, systems, and methods described herein relate to determining a concentration of a species of interest in a sample by using a spectrometer.
Amit Kumar Dutta
Filed: 11 Jan 22
Utility
Pressure Gauge Relief Valve
5 Jan 23
A pressure gauge and/or relief valve which may be used in a single-use fluid system, such as a sterilizable fluid system.
Travis R. Ward
Filed: 29 Jun 22
Utility
Encapsulated system for pressurized fluid processes
20 Dec 22
Fluid management systems for handling pressurized fluid connect various subsystems or subunits without the need to use reinforced tubing.
Michael C. Gagne, Dean C. Richards, Steven V. Cates
Filed: 20 Jul 22
Utility
Fluid plug for sterile processes and methods of using the same
20 Dec 22
A fluid plug for use with sterile processes such as the manufacture or production of pharmaceuticals and biologics is disclosed.
Michael C. Gagne
Filed: 13 Jan 21
Utility
Devices, systems, and methods for continuous processing with alternating tangential flow
13 Dec 22
The present disclosure relates to tangential flow filters, membranes, and ultrafiltration membranes, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.
Mark A. Perreault
Filed: 28 Jul 20
Utility
Devices, systems, and methods for a reducer with an integrated seal
6 Dec 22
The present disclosure is related to bioprocessing devices, systems, and methods, and particularly to sanitary connections for bioprocessing.
Derek Carroll, Bao Le
Filed: 29 Oct 19
Utility
Filtration cassette residing in bag and methods of using same
29 Nov 22
Tangential flow filtration systems utilizing flexible bags for permeate collection are provided.
Mark A. Perreault
Filed: 24 Nov 20
Utility
Fluid monitoring assembly with replaceable sensor functionality
29 Nov 22
A fluid monitoring assembly includes a conduit having a wall defining a lumen for carrying fluid.
Michael C. Gagne, Steven V. Cates, Dean C. Richards, Scott Bendon
Filed: 13 Apr 21
Utility
Dual Pumping Arrangement for a Hollow Fiber Filter
17 Nov 22
A fluid filtration assembly includes a filter housing having first and second ends and a connector for fluid communication with a fluid storage vessel.
Rudolf Pavlik
Filed: 2 Aug 22
Utility
Plunger Pumping Arrangement for a Hollow Fiber Filter
10 Nov 22
A fluid filtration assembly includes a filter housing having a first end for fluid connection with a fluid storage vessel.
Rudolf Pavlik
Filed: 20 Jul 22
Utility
Encapsulated Valve System and Method of Use
10 Nov 22
An encapsulated valve system includes a first housing portion having a first facing surface, the first facing surface comprising a plurality of branch pathways formed as a recess within the first facing surface.
Michael C. Gagne, Steven V. Cates
Filed: 20 Jul 22
Utility
Encapsulated System for Pressurized Fluid Processes
10 Nov 22
Fluid management systems for handling pressurized fluid connect various subsystems or subunits without the need to use reinforced tubing.
Michael C. Gagne, Dean C. Richards, Steven V. Cates
Filed: 20 Jul 22
Utility
Methods of Preparing Viral Vectors
27 Oct 22
This disclosure relates generally to process filtration systems, and more particularly to systems utilizing tangential flow filtration.
Amit Kumar Dutta, James Ronald Peyser
Filed: 10 Dec 20
Utility
Filtration System and Method
20 Oct 22
A fluid filtration system includes a fluid storage vessel such as a bioreactor, a filter housing including a filter element disposed therein, a pump coupled between the fluid storage vessel and the filter housing, and a flow diverter disposed between the pump and the filter housing.
Rudolf Pavlik, Ralf Kuriyel
Filed: 15 Apr 22
Utility
Filtration System and Method
20 Oct 22
A fluid filtration system includes a fluid storage vessel such as a bioreactor, a filter housing including a filter element disposed therein, a pump coupled between the fluid storage vessel and the filter housing, and a flow diverter disposed between the pump and the filter housing.
Rudolf Pavlik, Ralf Kuriyel
Filed: 29 Jun 22
Utility
Systems and Methods for Tangential Flow Depth Filtration
13 Oct 22
The present disclosure relates to hollow fiber tangential flow filter units, including hollow fiber tangential flow depth filter units, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.
Michael Bransby, Philip Yuen, Rene Daniel Jean-Marie Gantier, David Bianchi, Jonathan Kuhlmann
Filed: 13 Apr 22
Utility
Method of Actuation of an Alternating Tangential Flow Diaphragm Pump
13 Oct 22
A control unit includes a first connector configured to connect a proportional pressure regulator to a positive pressure supply and a second connector configured to connect the proportional pressure regulator to a negative pressure supply.
Rudolf Pavlik
Filed: 24 May 22