187 patents
Page 10 of 10
Utility
Multiple Oligonucleotide Moieties on Peptide Carrier
25 Dec 19
The present disclosure relates to antisense oligonucleotides (AONs), such as phosphorodiamidate morpholino oligonucleotides (PMOs).
Timothy E. WEEDEN, Carol A. NELSON, Bruce M. WENTWORTH, Nicholas P. CLAYTON, Andrew LEGER
Filed: 31 Jan 19
Utility
Fusion Proteins Comprising PDGF and Vegf Binding Portions and Methods of Using Thereof
13 Nov 19
The present provides fusion proteins comprising PDGF and VEGF binding portions, and recombinant viral particles encoding the fusion proteins.
Peter Pechan, Jeffery Ardinger, Hillard Rubin, Samuel Wadsworth, Abraham Scaria
Filed: 19 Nov 18
Utility
Perfusion Bioreactor With Filtration Systems
6 Nov 19
The disclosure provides a filtration system for a cell culture apparatus and a method of cell culture.
Jiuyi Lu, Jason Walther, Jonathan Wang, Kevin Victor Chen
Filed: 2 May 19
Utility
Slow Intraventricular Delivery
30 Oct 19
Neurological diseases, including lysosomal storage diseases, can be successfully treated using intraventricular delivery of the therapeutic agents to bypass the blood-brain barrier.
James C. DODGE, Marco A. PASSINI, Lamya S. SHIHABUDDIN, Seng H. CHENG
Filed: 20 Feb 19
Utility
Synthesis of Udp-glucose: N-acylsphingosine Glucosyltransferase Inhibitors
23 Oct 19
Disclosed is a novel enantiomeric synthesis ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase.
Bradford H. HIRTH, Craig Siegel
Filed: 20 Nov 18
Utility
Aav Virions with Decreased Immunoreactivity and Uses Therefor
16 Oct 19
Methods of making and using recombinant AAV virions with decreased immunoreactivity are described.
Alejandra E. ARBETMAN, Peter C. COLOSI, Michael A. LOCHRIE, Richard T. SUROSKY
Filed: 28 Jan 19
Utility
Novel Beta-actin and RPS21 Promoters and Uses Thereof
2 Oct 19
The invention relates to isolation of novel β-actin and ribosomal protein S21 (rpS21) promoters and uses thereof.
Scott D. ESTES, Weiqun ZHANG
Filed: 11 Mar 19