Soligenix (SNGX) USPTO patents

Utility

Compositions and Methods of Manufacturing Trivalent Filovirus Vaccines

23 Mar 23

Disclosed is a stable immunogenic composition capable of eliciting a robust and durable immune response, comprising at least one antigen consisting of a filovirus glycoprotein and at least one nano-emulsion adjuvant which are co-lyophilized and can be reconstituted immediately prior to use.

Oreola Donini, Axel Lehrer

Filed: 2 Sep 22

Utility

Dermatological Compositions and Methods of Treatment against Cutaneous T-Cell Lymphoma

26 Jan 23

A method of treating CTCL comprising applying a combination of an effective amount of hypericin together with a form of visible light photodynamic therapy.

Oreola Donini, Richard Straube, Christopher Schaber

Filed: 8 Jul 22

Utility

Compositions and methods of manufacturing trivalent filovirus vaccines

6 Sep 22

Disclosed is a stable immunogenic composition capable of eliciting a robust and durable immune response, comprising at least one antigen consisting of a filovirus glycoprotein and at least one nano-emulsion adjuvant which are co-lyophilized and can be reconstituted immediately prior to use.

Oreola Donini, Axel Lehrer

Filed: 20 May 20

Utility

Peptides and analogs for use in the treatment of oral mucositis

26 Apr 22

Preclinical data obtained in models of chemotherapy-induced mucositis, radiation-induced mucositis, neutropenic infection and colitis indicate oral mucositis is a promising indication for Innate Defense Regulator (IDR) peptides.

Oreola Donini, Annett Rozek, Jackson Lee, John North, Michael Abrams

Filed: 9 Apr 19

Utility

Thermostable Vaccine Compositions and Methods of Preparing same

25 Nov 21

Compositions relating to thermostable vaccines and methods of preparing the same.

Kimberly Hassett, Pradyot Nandi, Robert N. Brey, John Carpenter, Theodore Randolph

Filed: 10 May 21

Utility

Compositions and Methods of Manufacturing Trivalent Filovirus Vaccines

2 Dec 20

Disclosed is a stable immunogenic composition capable of eliciting a robust and durable immune response, comprising at least one antigen consisting of a filovirus glycoprotein and at least one nano-emulsion adjuvant which are co-lyophilized and can be reconstituted immediately prior to use.

Oreola Donini, Axel Lehrer

Filed: 19 May 20

Utility

Novel Peptides and Analogs for Use in the Treatment of Oral Mucositis

14 Oct 20

Preclinical data obtained in models of chemotherapy-induced mucositis, radiation-induced mucositis, neutropenic infection and colitis indicate oral mucositis is a promising indication for Innate Defense Regulator (IDR) peptides.

Oreola Donini, Annett Rozek, Jackson Lee, John Carpenter, Michael Abrams

Filed: 8 Apr 19

Utility

Topically Active Steroids for Use in Radiation and Chemotherapeutics Injury

20 May 20

Methods of delivering corticosteroids or metabolites thereof for treating and preventing tissue damage resulting from acute radiation injury in the gastrointestinal tract with locally effective therapeutic agents.

Robert N. Brey, Christopher Schaber, George McDonald

Filed: 20 Jun 19

Utility

Systems and methods for producing synthetic hypericin

6 Jan 20

Improved systems and methods for producing synthetic hypericin at high volume and high purity.

Rasappa Arumugham, Christopher Schaber, Holger Rauter, Silvia Werner

Filed: 20 Aug 18