121 patents
Utility
Treating headache comprising administering an antibody to calcitonin gene-related peptide
17 Jan 23
The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms and/or headaches (e.g., migraine, cluster headache, and tension headache) by administering an anti-CGRP antagonist antibody.
Marcelo Bigal, Sarah Walter, Henry Stern, Michael Chang
Filed: 7 Nov 19
Utility
Injection spring for aged prefilled syringe and auto injector
3 Jan 23
A method of adapting an auto injector configured to actuate a prefilled syringe, the auto injector having a biasing member having a spring constant, the prefilled syringe being filled with a volume of therapeutic fluid, the prefilled syringe including a barrel, stopper, and a needle, the stopper having a path of travel, the biasing member arranged to move the stopper along the path of travel.
Paul Andrew Christopher Gibson, Edward Andrew Cummings
Filed: 19 Sep 19
Utility
Solid State Forms of Lucerastat and Process for Preparation Thereof
29 Dec 22
The present disclosure encompasses solid state forms of Lucerastat, in embodiments crystalline Lucerastat: L-Pyroglutamic acid, crystalline Lucerastat: Salicylic acid, crystalline Lucerastat: Fumaric acid, crystalline Lucerastat: Benzoic acid and crystalline Lucerastat: o-Acetylsalicylic acid, solid state form thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Yogesh Dhananjay Wagh
Filed: 23 Sep 20
Utility
Solid State Forms of Fezagepras and Process for Preparation Thereof
1 Dec 22
The present disclosure encompasses solid state forms of Setogepram, in embodiments crystalline polymorphs or salts of Setogepram, particularly Setogepram sodium, processes for preparation thereof, and pharmaceutical compositions thereof.
Anantha Rajmohan Muthusamy, Amit Singh, Venkata Subbarao Yazali
Filed: 27 Oct 20
Utility
Solid State Forms of ARRY-797 and Process for Preparation Thereof
1 Dec 22
The present disclosure encompasses solid state forms of Arry-797, in embodiments crystalline polymorphs or salts or co-crystals of Arry-797, processes for preparation thereof, and pharmaceutical compositions thereof.
Dijana Skalec Samec, Valentina Travancic
Filed: 28 Oct 20
Utility
Solid State Forms of Pemafibrate
24 Nov 22
The present disclosure relates to solid state forms of Pemafibrate processes for preparation thereof and pharmaceutical compositions thereof.
Pavel Kolesa, Andrea Colombo, Ettore Marzorati
Filed: 19 Jul 22
Utility
Solid State Forms of Roluperidone and Salts Thereof
10 Nov 22
The present disclosure relates to solid state forms of roluperidone and salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
Dijana Skalec Samec, Lorena Kordic
Filed: 29 Jun 20
Utility
Processes for the Preparation of Roxadustat and Intermediates Thereof
27 Oct 22
Parven Kumar Luthra, Suhail Ahmad, Neval Kishor, Miteshgir Kanchangir Goswami, Alok Singh, Chandrasekhar Sinha, Syed Aziz Imam Quadri, Prashant Shankar Joshi, Sadanand Hardeo Maurya
Filed: 6 Aug 20
Utility
Sustained Release Olanzapine Formulations
13 Oct 22
The disclosure is directed to methods of treating schizophrenia or bipolar disorder by subcutaneously administering a sustained-release dosage form of olanzapine, or a pharmaceutically acceptable salt thereof.
Mark Alan Smith, Carine Claassen-Punt
Filed: 23 Jun 22
Utility
Solid State Forms of Risdiplam and Process for Preparation Thereof
6 Oct 22
The present disclosure encompasses solid state forms of Risdiplam, including crystalline polymorphs of Risdiplam, processes for preparation thereof, and pharmaceutical compositions thereof.
Sanja Matecic Musanic, Dario Klaric, Mateja Kolenic
Filed: 28 Jul 20
Utility
Solid state forms of Pemafibrate
23 Aug 22
The present disclosure relates to solid state forms of Pemafibrate processes for preparation thereof and pharmaceutical compositions thereof.
Pavel Kolesa, Andrea Colombo, Ettore Marzorati
Filed: 21 Dec 18
Utility
Solid State Forms of Tafamidis and Salts Thereof
18 Aug 22
The present disclosure relates to solid state forms of Tafamidis and salts thereof, processes for preparation thereof and pharmaceutical compositions thereof.
Sanja MATECIC MUSANIC, Valentina TRAVANCIC, Dubravka PAVLICIC
Filed: 15 May 20
Utility
Solid State Forms of Relugolix
21 Jul 22
The present disclosure provides solid state forms of Relugolix, crystalline forms of Relugolix, pharmaceutical compositions thereof, and pharmaceutical formulations thereof.
Hana Kantor, Roman Gabriel, Pavel Kolesa, Alexandr Jegorov
Filed: 6 Apr 22
Utility
Solid State Forms of SAGE-217 and Processes for Preparation Thereof
14 Jul 22
The present disclosure encompasses solid state forms of SAGE-217, in embodiments SAGE-217:Oxalic acid Co-crystal, processes for preparation thereof, and pharmaceutical compositions thereof.
Polina Lapido, Ofir Shaul, Firas Masri
Filed: 14 May 20
Utility
Solid state forms of lumateperone ditosylate salt
17 May 22
Disclosed are solid state forms of lumateperone ditosylate, uses thereof, and pharmaceutical compositions thereof.
Ariel Mittelman, Ido Fuchs, Sharona Shachantov, Doron Rudik, Rotem Sella-Erez
Filed: 8 Aug 17
Utility
Solid State Forms of Ripretinib
12 May 22
The present disclosure relates to solid state forms of ripretinib, processes for preparation thereof, as well as a pharmaceutical composition including the same.
Sanja Matecic Musanic, Lara Jurkovic, Valentina Travancic
Filed: 11 Mar 20
Utility
Solid State Forms of N-[2-(2-{4-[2-(6,7-DIMETHOXY-3,4-DIHYDRO-2(1H)-ISOQUINOLINYL)ETHYL]PHENYL}-2H-TETRAZOL-5-YL)-4,5- DIMETHOXYPHENYL]-4-OXO-4H-CHROMENE-2-CARBOXAMIDE and of Its Mesylate Salt
5 May 22
The present disclosure relates to solid state forms of Encequidar (previously referred to as HM-30181A) base, Encequidar ((HM-30181A) mesylate, co-crystals of Encequidar (HM-30181A) mesylate, processes for preparation thereof, as well as pharmaceutical compositions including the same.
Petar Bibuliç, Dijana Skalec Samec, Marina Marinkovic, Jasna Dogan
Filed: 14 Feb 20
Utility
Crystalline Solid Forms of Baricitinib
5 May 22
The present disclosure relates to cocrystals/salts of baricitinib, processes for preparation thereof as well as a pharmaceutical composition comprising the same.
Ivana Landeka, Dijana Skalec Samec, Lorena Kordic
Filed: 5 Feb 20
Utility
Solid State Forms of Lumateperone Ditosylate Salt
28 Apr 22
Disclosed are solid state forms of lumateperone ditosylate, uses thereof, and pharmaceutical compositions thereof.
Ariel MITTELMAN, Ido FUCHS, Sharona SHACHANTOV, Doron RUDIK, Rotem SELLA-EREZ
Filed: 7 Jan 22
Utility
Solid state forms of Relugolix
19 Apr 22
The present disclosure provides solid state forms of Relugolix, crystalline forms of Relugolix, pharmaceutical compositions thereof, and pharmaceutical formulations thereof.
Hana Kantor, Roman Gabriel, Pavel Kolesa, Alexandr Jegorov
Filed: 14 Mar 19