182 patents
Utility
Compositions and methods for treating diseases of the nail
16 Jan 24
Methods and compositions for treating disorders of the nail and nail bed.
Gareth Winckle, Gregory T. Fieldson
Filed: 23 Dec 21
Utility
Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
4 Jan 24
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer).
Kunwar Shailubhai, Gary S. Jacob
Filed: 20 Mar 23
Utility
Rifaximin Liquid Formulations for Use Inthe Treatment of Sickle Cell Disease
14 Dec 23
Pharmaceutical composition comprising rifaximin, a hydrogenated castor oil, and at least one additional solubilizing excipient for use in the treatment of sickle cell disease, vaso-occlusive crises or circulating ages neutrophils.
Arturo J. Angel, Kasturi R. Pawar, Radhakrishnan S. Pillai
Filed: 29 Oct 21
Utility
Pharmaceutical formulations containing corticosteroids for topical administration
12 Dec 23
Pharmaceutical compositions for topical application to skin are provided.
Arturo Angel, Gordon Dow
Filed: 23 Nov 22
Utility
Redundant traces for flexible circuits used in an energy delivery device
12 Dec 23
Energy delivery devices with a flexible circuit.
Craig Collins, Kurt Duclos, Martin Kenney
Filed: 1 Feb 22
Utility
Tissue treatment apparatus and systems with pain mitigation and methods for mitigating pain during tissue treatments
5 Dec 23
Methods, apparatus, and systems for delivering electromagnetic energy to a patient's tissue with a reduction in the pain experienced by the patient.
Dragan D. Nebrigic, Thomas Markiewicz
Filed: 29 Jan 21
Utility
Ultra-pure agonists of guanylate cyclase C, method of making and using same
5 Dec 23
The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein.
Kunwar Shailubhai, Stephen Comiskey, Rong Feng, Juncai Bai, Ruoping Zhang, Jun Jia, Junfeng Zhou, Qiao Zhao, Guoqing Zhang
Filed: 30 Mar 23
Utility
Topical Compositions and Methods for Treating Psoriasis
9 Nov 23
Topical pharmaceutical compositions comprise a combination of a corticosteroid a retinoid; and methods for treating psoriasis with same.
Gordon J. DOW, Radhakrishnan PILLAI, Varsha D. BHATT
Filed: 4 May 23
Utility
Ultra-pure Agonists of Guanylate Cyclase C, Method of Making and Using Same
26 Oct 23
The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein.
Kunwar Shailubhai, Stephen Comiskey, Rong Feng, Juncai Bai, Ruoping Zhang, Jun Jia, Junfeng Zhou, Qiao Zhao, Guoqing Zhang
Filed: 30 Mar 23
Utility
Methods of Treating Hepatic Encephalopathy
19 Oct 23
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics.
William Forbes
Filed: 18 Apr 23
Utility
Methods for treating irritable bowel syndrome (IBS)
10 Oct 23
The present invention provides new methods and kits for treating IBS; treating IBS in females; treating IBS in older subjects; and treating IBS in non-white subjects.
William Forbes, Enoch Bortey
Filed: 10 Mar 21
Utility
Anti-infective Methods, Compositions, and Devices
21 Sep 23
The present invention provides methods for treating onychomycosis.
Radhakrishnan PILLAI, Gordon DOW
Filed: 12 Apr 23
Utility
Targeted Release Rifaximin Compositions
7 Sep 23
Provided herein are GI specific rifaximin release compositions which can be formulated for targeted delivery of rifaximin to one or more portions of the GI tract.
Jacob Cole, Brian R. Rohrs, Daniel J. Stein, Robert J. Israel, Ezra R. Lowe
Filed: 25 Jun 21
Utility
Ocular drug delivery devices
22 Aug 23
A method of forming an ocular delivery device includes exposing a solid, shaped cellulose polymer to a solution including an active pharmaceutical ingredient (API) and a solvent capable of solubilizing the API, wherein the polymer absorbs at least a portion of the solution, including the API and solvent.
Jean Theresa Jacob, Kevin John Halloran, Yuri McKee
Filed: 7 Jan 19
Utility
Pain mitigation by mechanical stimulation when treating tissue with electromagnetic energy
8 Aug 23
Apparatus and methods for delivering electromagnetic energy to a patient's tissue and reducing pain experienced by the patient during treatment of the patient's tissue with the delivered electromagnetic energy.
Craig Robert Bockenstedt, Gregory T. Wing
Filed: 30 Aug 19
Utility
Formulations of Calcium and Phosphate for Oral Inflammation
3 Aug 23
The present invention generally relates to liquid compositions and methods for treating oral inflammation by administering a liquid composition to the oral cavity.
Bartholomew Weldon, Edward Kobus, Sandryne Dumoulin, Aimesther Betancourt, Patrick Gosselin
Filed: 24 Feb 23
Utility
Solid dispersion forms of rifaximin
30 May 23
Provided herein are solid dispersions comprising rifaximin and pharmaceutical compositions and uses thereof.
Pam Golden, Mohammed A. Kabir
Filed: 7 Sep 21
Utility
Anti-infective methods, compositions, and devices
23 May 23
The present invention provides methods for treating onychomycosis.
Radhakrishnan Pillai, Gordon Dow
Filed: 5 Oct 20
Utility
Methods of Reducing Mortality In Subjects Suffering from an Underlying Disease or Condition by Administration of Methylnaltrexone
18 May 23
The present disclosure is directed to the use of methylnaltrexone or a salt thereof or an ion pair thereof for reducing mortality in a subject suffering from an underlying disease or condition (e.g., advanced illness, cancer, a chronic non-cancer pain, postoperative ileus, or recovery from orthopedic surgery).
Neal Slatkin
Filed: 13 Oct 22
Utility
Topical compositions and methods for treating psoriasis
16 May 23
Topical pharmaceutical compositions comprise a combination of a corticosteroid a retinoid; and methods for treating psoriasis with same.
Gordon J. Dow, Radhakrishnan Pillai, Varsha D. Bhatt
Filed: 23 Nov 22