34 patents
Utility
Method of using biomarkers and clinical variables for predicting chemotherapy benefit
22 Nov 22
Provided herein are methods for predicting chemotherapy benefit.
Alexander Gutin, Julia Reid, Ralf Kronenwett, Marsel Scheer
Filed: 4 Mar 20
Utility
Gene Signatures for Cancer Prognosis
18 Aug 22
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia E. Reid
Filed: 23 Feb 22
Utility
Methods of Detecting Cancer
4 Aug 22
Methods and compositions involving molecular markers for the detection and characterization of cancer in a patient are provided.
Alexander Gutin, Jerry Lanchbury, Susanne Wagner, Victor Abkevich
Filed: 13 Jan 22
Utility
Methods and Materials for Assessing Allelic Imbalance
30 Jun 22
Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 8 Dec 21
Utility
Detecting Cancer Risk
30 Jun 22
The present disclosure relates to methods, kits, and systems for assessing the risk of a human subject for developing a cancer, including genetic risk assessment, clinical risk assessment, and combinations of both to improve risk analysis.
Elisha Hughes, Alexander Gutin
Filed: 4 Oct 21
Utility
Methods and Materials for Assessing Loss of Heterozygosity
30 Jun 22
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature.
Victor Abkevich, Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 12 Oct 21
Utility
Gene Signatures for Cancer Prognosis
14 Apr 22
Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.
Steven Stone, Alexander Gutin, Julia Reid
Filed: 24 Sep 21
Utility
Copy number variant caller
25 Jan 22
Direct targeted sequencing (DTS) methods and a hidden Markov model (HMM) can be used to call the copy number of a segment of interest within a region of interest.
Kevin R. Haas, Xin Wang, Peter V. Grauman
Filed: 23 Mar 18
Utility
Methods and materials for assessing allelic imbalance
18 Jan 22
Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 11 Mar 20
Utility
Gene signatures for cancer prognosis
16 Nov 21
Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.
Steven Stone, Alexander Gutin, Julia Reid
Filed: 11 Nov 16
Utility
Method of treating cancer
16 Nov 21
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature.
Victor Abkevich, Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 21 Nov 19
Utility
Hereditary Cancer Genes
11 Nov 21
The invention generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
Kirsten Timms, Brian Allen, Anne-Renee Hartman
Filed: 22 Jul 21
Utility
Methods and Materials for Assessing Homologous Recombination Deficiency
7 Oct 21
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature.
Victor Abkevich, Kirsten Timms, Alexander Gutin
Filed: 21 Jun 21
Utility
Hereditary cancer genes
31 Aug 21
The invention generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
Kirsten Timms, Brian Allen, Anne-Renee Hartman
Filed: 5 Dec 14
Utility
Methods and Systems for Somatic Mutations and Uses Thereof
26 Aug 21
This invention provides methods and compositions for detecting somatic mutations in cancer cells.
Andrey ZHARKIKH, Kirsten TIMMS, Michael PERRY, Alexander GUTIN
Filed: 6 May 21
Utility
Genes and gene signatures for diagnosis and treatment of melanoma
1 Jun 21
Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma.
Michael Bryan Warf, Benjamin Roa, Alexander Gutin, Darl Flake
Filed: 12 Mar 14
Utility
Gene signatures for cancer prognosis
23 Mar 21
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia E. Reid
Filed: 26 Feb 15
Utility
Gene Signatures for Cancer Prognosis
11 Mar 21
Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia Reid
Filed: 12 Nov 20
Utility
Gene signatures for cancer prognosis
28 Dec 20
Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia Reid
Filed: 14 May 15
Utility
Methods and Materials for Assessing Loss of Heterozygosity
23 Dec 20
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature.
Victor Abkevich, Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 3 Sep 20