| Date | Company | Security | Transaction | Code | Indirect | 10b5-1 | $Price | #Shares | $Value | #Remaining |
|---|---|---|---|---|---|---|---|---|---|---|
| 16 Jan 25 | IONS Ionis Pharmaceuticals | Common Stock | Sell | Dispose S | No | No | 32.806 | 8,870 | 290.99 k | 107,885 |
| 15 Jan 25 | IONS Ionis Pharmaceuticals | Common Stock | Option exercise | Acquire M | No | No | 0 | 23,887 | 0.00 | 116,755 |
| 15 Jan 25 | IONS Ionis Pharmaceuticals | RSU Common Stock | Option exercise | Dispose M | No | No | 0 | 23,887 | 0.00 | 84,669 |
| 15 Jan 25 | IONS Ionis Pharmaceuticals | RSU Common Stock | Grant | Acquire A | No | No | 0 | 46,500 | 0.00 | 108,556 |
| 15 Jan 25 | IONS Ionis Pharmaceuticals | RSU Common Stock | Grant | Acquire A | No | No | 0 | 31,000 | 0.00 | 86,635 |
| 2 Jan 25 | IONS Ionis Pharmaceuticals | NQSO Common Stock | Grant | Acquire A | No | No | 34.69 | 31,000 | 1.08 mm | 31,000 |
| 2 Feb 24 | IONS Ionis Pharmaceuticals | Common Stock | Sell | Dispose S | No | No | 49.5399 | 2,162 | 107.11 k | 92,868 |
| 2 Feb 24 | IONS Ionis Pharmaceuticals | Common Stock | Sell | Dispose S | No | No | 49.5399 | 2,125 | 105.27 k | 92,905 |
| 1 Feb 24 | IONS Ionis Pharmaceuticals | Common Stock | Grant | Acquire A | No | No | 0 | 4,140 | 0.00 | 95,030 |
