Joseph Shulman

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
11 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	67.8343	700	47.48 k	0
11 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	67.054	5,977	400.78 k	700
11 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	65.7291	6,604	434.07 k	6,677
11 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	21.38	5,312	113.57 k	13,281
11 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	6.8	7,969	54.19 k	7,969
11 Nov 24	RYTM Rhythm Pharmaceuticals	Stock Option Common Stock	Option exercise	Dispose M	No	No	21.38	5,312	113.57 k	0
11 Nov 24	RYTM Rhythm Pharmaceuticals	Stock Option Common Stock	Option exercise	Dispose M	No	No	6.8	7,969	54.19 k	19,922
16 Jul 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	53.0012	10,468	554.82 k	30
16 Jul 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	27.35	10,468	286.30 k	10,498
16 Jul 24	RYTM Rhythm Pharmaceuticals	Stock Option Common Stock	Option exercise	Dispose M	No	No	27.35	10,468	286.30 k	23,032

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.