Edward Morrow Atkinson III

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
11 Feb 25	VRTX Vertex Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	459.83	1,747	803.32 k	23,225
10 Feb 25	VRTX Vertex Pharmaceuticals	Common Stock	Payment of exercise	Dispose F	No	No	467.98	876	409.95 k	24,972
4 Feb 25	VRTX Vertex Pharmaceuticals	Common Stock	Grant	Acquire A	No	No	0	4,744	0.00	25,848
4 Feb 25	VRTX Vertex Pharmaceuticals	Common Stock	Grant	Acquire A	No	No	0	5,132	0.00	21,104
3 Feb 25	ETNB 89bio	Stock Option Common Stock	Grant	Acquire A	No	No	9.6	56,400	541.44 k	56,400
12 Jun 24	VRTX Vertex Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	478	7,288	3.48 mm	15,972
11 Jun 24	VRTX Vertex Pharmaceuticals	Common Stock	Payment of exercise	Dispose F	No	No	481.96	6,824	3.29 mm	23,260
14 May 24	VRTX Vertex Pharmaceuticals	Common Stock	Grant	Acquire A	No	No	0	14,112	0.00	30,084

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.