Alexandra Hughes-Wilson

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
25 Jan 25	MREO Mereo BioPharma	Share Options American Depository Shares	Grant	Acquire A	No	No	2.91	154,000	448.14 k	154,000
13 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Sell	Dispose S	No	No	4.221	84,008	354.60 k	50,475
13 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Sell	Dispose S	No	No	4.221	16,304	68.82 k	134,483
12 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Sell	Dispose S	No	No	4.4727	40,029	179.04 k	150,787
12 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Sell	Dispose S	No	No	4.4727	7,769	34.75 k	190,816
11 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Option exercise	Acquire M	No	No	1.01	75,000	75.75 k	242,881
11 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Option exercise	Acquire M	No	No	1.4	93,333	130.67 k	167,881
11 Sep 24	MREO Mereo BioPharma	American Depositary Shares representing Ordinary Shares	Option exercise	Acquire M	No	No	0	40,000	0.00	74,548
11 Sep 24	MREO Mereo BioPharma	Share Options American Depository Shares	Option exercise	Dispose M	No	No	1.01	75,000	75.75 k	0
11 Sep 24	MREO Mereo BioPharma	Share Options American Depository Shares	Option exercise	Dispose M	No	No	1.4	93,333	130.67 k	0

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.