Pyott David E I

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
24 Jun 24	ALNY Alnylam Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	222	7,470	1.66 mm	136
24 Jun 24	ALNY Alnylam Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	221	7,420	1.64 mm	7,606
24 Jun 24	ALNY Alnylam Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	220	17,560	3.86 mm	15,026
24 Jun 24	ALNY Alnylam Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	Yes	71.99	7,470	537.77 k	32,586
24 Jun 24	ALNY Alnylam Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	Yes	70.2	7,420	520.88 k	25,116
24 Jun 24	ALNY Alnylam Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	Yes	88.95	17,560	1.56 mm	17,696
24 Jun 24	ALNY Alnylam Pharmaceuticals	Stock Option Common Stock	Option exercise	Dispose M	No	Yes	88.95	17,560	1.56 mm	7,440
24 Jun 24	ALNY Alnylam Pharmaceuticals	Stock Option Common Stock	Option exercise	Dispose M	No	Yes	71.99	7,470	537.77 k	3,780
24 Jun 24	ALNY Alnylam Pharmaceuticals	Stock Option Common Stock	Option exercise	Dispose M	No	Yes	70.2	7,420	520.88 k	3,830
13 Jun 24	PLRX Pliant Therapeutics	Common Stock Common Stock	Grant	Acquire A	No	No	13.06	26,764	349.54 k	26,764

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.