Meeker David P

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
19 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	57.22	9,896	566.25 k	201,281
16 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	0	21,250	0.00	211,177
16 Feb 25	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Option exercise	Dispose M	No	No	0	21,250	0.00	63,750
14 Feb 25	RYTM Rhythm Pharmaceuticals	Stock Options Common Stock	Grant	Acquire A	No	No	56.69	200,000	11.34 mm	200,000
14 Feb 25	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Grant	Acquire A	No	No	0	133,350	0.00	133,350
4 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	59.43	4,278	254.24 k	189,927
1 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	0	14,125	0.00	194,205
1 Feb 25	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Option exercise	Dispose M	No	No	0	14,125	0.00	28,250
27 Aug 24	TRVI Trevi Therapeutics	Common Stock	Sell	Dispose S	No	No	2.9314	4,555	13.35 k	352,489
27 Aug 24	TRVI Trevi Therapeutics	Common Stock	Option exercise	Acquire M	No	No	1.43	4,555	6.51 k	357,044

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.