Mardi Dier

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
9 May 23	SLRN Acelyrin	Common Stock	Buy	Acquire P	Yes	No	18	875	15.75 k	875
9 May 23	SLRN Acelyrin	Common Stock	Buy	Acquire P	Yes	No	18	875	15.75 k	875
9 May 23	SLRN Acelyrin	Common Stock	Buy	Acquire P	No	No	18	5,556	100.01 k	5,556
9 May 23	SLRN Acelyrin	Employee Stock Option Common Stock	Other	Acquire J	No	No	18	85,226	1.53 mm	85,226
9 May 23	SLRN Acelyrin	Employee Stock Option Class A Common Stock	Other	Dispose J	No	No	18	85,226	1.53 mm	0
9 May 23	SLRN Acelyrin	Employee Stock Option Common Stock	Other	Acquire J	No	No	5.8766	673,621	3.96 mm	673,621
9 May 23	SLRN Acelyrin	Employee Stock Option Class A Common Stock	Other	Dispose J	No	No	5.8766	673,621	3.96 mm	0
4 May 23	SLRN Acelyrin	Employee Stock Option Class A Common Stock	Grant	Acquire A	No	No	18	85,226	1.53 mm	85,226
14 Oct 22	RARE Ultragenyx Pharmaceutical	Common Stock	Sell	Dispose S	No	Yes	40.16	1,629	65.42 k	66,695
12 Oct 22	RARE Ultragenyx Pharmaceutical	Common Stock	Sell	Dispose S	No	No	38.22	3,484	133.16 k	68,324

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.