Witz Pascale

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
20 May 24	RGLS Regulus Therapeutics	Stock Option Common Stock	Grant	Acquire A	No	No	2.01	60,000	120.60 k	60,000
16 May 24	RGLS Regulus Therapeutics	Stock Option Common Stock	Grant	Acquire A	No	No	2.01	30,000	60.30 k	30,000
1 May 24	RVTY Revvity	Common Stock	Grant	Acquire A	No	No	0	1,218	0.00	11,293
1 May 24	RVTY Revvity	Common Stock	Grant	Acquire A	No	No	0	977	0.00	10,075
6 Oct 23	HZNP Horizon Therapeutics Public	Ordinary Shares	Sale back to company	Dispose D	Yes	No	116.5	20,279	2.36 mm	0
6 Oct 23	HZNP Horizon Therapeutics Public	Ordinary Shares	Sale back to company	Dispose D	No	No	116.5	25,672	2.99 mm	0
6 Oct 23	HZNP Horizon Therapeutics Public	RSU Ordinary Shares	Sale back to company	Dispose D	No	No	0	4,016	0.00	0
6 Oct 23	HZNP Horizon Therapeutics Public	Stock Option Ordinary Shares	Sale back to company	Dispose D	No	No	13.87	32,161	446.07 k	0
6 Oct 23	HZNP Horizon Therapeutics Public	Stock Option Ordinary Shares	Sale back to company	Dispose D	No	No	12.19	52,232	636.71 k	0
10 Aug 23	RGLS Regulus Therapeutics	Stock Option Common Stock	Grant	Acquire A	No	No	1.36	15,000	20.40 k	15,000

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.