Allene M. Diaz

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
16 Jul 24	IONS Ionis Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	50.17	737	36.98 k	15,716
16 Jul 24	IONS Ionis Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	48.9379	900	44.04 k	16,453
15 Jul 24	IONS Ionis Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	0	4,677	0.00	17,353
15 Jul 24	IONS Ionis Pharmaceuticals	RSU Common Stock	Option exercise	Dispose M	No	No	0	4,677	0.00	4,079
1 Jul 24	IONS Ionis Pharmaceuticals	RSU Common Stock	Grant	Acquire A	No	No	0	4,079	0.00	8,756
1 Jul 24	IONS Ionis Pharmaceuticals	NQSO Common Stock	Grant	Acquire A	No	No	47.11	10,111	476.33 k	10,111
11 Jun 24	MRSN Mersana Therapeutics	Stock Option Common Stock	Grant	Acquire A	No	No	2.26	55,000	124.30 k	55,000

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.