Michael Thomas Henderson

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
5 Feb 25	APGE Apogee Therapeutics	Common Stock	Sell	Dispose S	No	Yes	40.58	15,000	608.70 k	1,302,987
31 Jan 25	APGE Apogee Therapeutics	Common Stock	Option exercise	Acquire M	No	No	22.86	8,500	194.31 k	1,317,987
31 Jan 25	APGE Apogee Therapeutics	Stock Option Common Stock	Option exercise	Dispose M	No	No	22.86	8,500	194.31 k	390,012
10 Jan 25	SYRE Spyre Therapeutics	Common Stock	Other	Acquire J	No	No	0	105,379	0.00	105,379
8 Jan 25	APGE Apogee Therapeutics	Common Stock	Sell	Dispose S	No	Yes	49.38	2,868	141.62 k	1,309,487
8 Jan 25	APGE Apogee Therapeutics	Common Stock	Sell	Dispose S	No	Yes	48.72	12,132	591.07 k	1,312,355
9 Dec 24	APGE Apogee Therapeutics	Stock Option Common Stock	Grant	Acquire A	No	No	49.07	357,036	17.52 mm	357,036

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.