Sath Shukla

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
5 Feb 25	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	0.78	106,408	83.00 k	1,736,883
5 Feb 25	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	0.78	42,786	33.37 k	1,843,291
5 Feb 25	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	0.78	6,139	4.79 k	1,886,077
3 Feb 25	SPRO Spero Therapeutics	Common Stock	Grant	Acquire A	No	No	0	751,407	0.00	1,892,216
27 Aug 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.35	2,757	3.72 k	1,140,809
5 Aug 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.31	17,641	23.11 k	1,143,566
2 Aug 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.32	14,800	19.54 k	1,161,207
5 Feb 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	Yes	1.45	45,093	65.38 k	1,176,007
2 Feb 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.37	30,901	42.33 k	1,221,100
1 Feb 24	SPRO Spero Therapeutics	Common Stock	Grant	Acquire A	No	No	0	679,501	0.00	1,252,001

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.