Timothy Keutzer

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
5 Feb 25	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	0.78	24,920	19.44 k	741,439
5 Feb 25	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	0.78	27,643	21.56 k	766,359
5 Feb 25	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	0.78	3,974	3.10 k	794,002
3 Feb 25	SPRO Spero Therapeutics	Common Stock	Grant	Acquire A	No	No	0	266,139	0.00	797,976
27 Aug 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.35	2,213	2.99 k	531,837
2 Feb 24	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.36	30,971	42.12 k	534,050
1 Feb 24	SPRO Spero Therapeutics	Common Stock	Grant	Acquire A	No	No	0	239,731	0.00	565,021
28 Aug 23	SPRO Spero Therapeutics	Common Stock	Sell	Dispose S	No	No	1.26	1,854	2.34 k	325,290

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.