Jennifer Chien

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
20 Mar 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	39.33	9,066	356.57 k	6,852
20 Mar 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	38.22	9,169	350.44 k	15,918
19 Mar 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	39.22	15,515	608.50 k	25,087
16 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Grant	Acquire A	No	No	0	33,750	0.00	40,602
16 Feb 24	RYTM Rhythm Pharmaceuticals	Stock Option Common Stock	Grant	Acquire A	No	No	49.23	67,000	3.30 mm	67,000
16 Feb 24	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Grant	Acquire A	No	No	0	22,000	0.00	22,000
13 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	49.83	615	30.65 k	6,852
12 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	51.38	1,023	52.56 k	7,467
11 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	0	2,031	0.00	8,490
11 Feb 24	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Option exercise	Dispose M	No	No	0	2,031	0.00	2,031

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.