Jennifer Chien

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
19 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	57.22	2,035	116.44 k	5,858
16 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	0	5,500	0.00	7,893
16 Feb 25	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Option exercise	Dispose M	No	No	0	5,500	0.00	16,500
14 Feb 25	RYTM Rhythm Pharmaceuticals	Stock Options Common Stock	Grant	Acquire A	No	No	56.69	55,000	3.12 mm	55,000
14 Feb 25	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Grant	Acquire A	No	No	0	36,650	0.00	36,650
13 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	58	1,205	69.89 k	2,393
12 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	56.39	1,205	67.95 k	3,598
12 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	56.41	10	564.10	4,803
12 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	56.39	600	33.83 k	4,813
11 Feb 25	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	57.5	4	230.00	5,413

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.