Pamela J. Cramer

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
7 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	65	4,688	304.72 k	13,500
7 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	19.02	4,688	89.17 k	18,188
7 Nov 24	RYTM Rhythm Pharmaceuticals	Stock Options Common Stock	Option exercise	Dispose M	No	No	19.02	4,688	89.17 k	14,062
6 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	60	4,687	281.22 k	13,500
6 Nov 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	19.02	4,687	89.15 k	18,187
6 Nov 24	RYTM Rhythm Pharmaceuticals	Stock Options Common Stock	Option exercise	Dispose M	No	No	19.02	4,687	89.15 k	18,750
9 Sep 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	50.0274	4,099	205.06 k	13,500
9 Sep 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	19.02	4,099	77.96 k	17,599
9 Sep 24	RYTM Rhythm Pharmaceuticals	Stock Options Common Stock	Option exercise	Dispose M	No	No	19.02	4,099	77.96 k	23,437
26 Aug 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	50.0056	3,200	160.02 k	13,500

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.