Remy Durand

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
20 May 24	ALPN Alpine Immune Sciences	Common Stock	Sale back to company	Dispose D	No	No	0	31,200	0.00	0
20 May 24	ALPN Alpine Immune Sciences	Common Stock	Sale back to company	Dispose D	No	No	0	102,192	0.00	31,200
20 May 24	ALPN Alpine Immune Sciences	Stock Option Common Stock	Sale back to company	Dispose D	No	No	18.33	78,000	1.43 mm	0
20 May 24	ALPN Alpine Immune Sciences	Stock Option Common Stock	Sale back to company	Dispose D	No	No	7.55	109,000	822.95 k	0
20 May 24	ALPN Alpine Immune Sciences	Stock Option Common Stock	Sale back to company	Dispose D	No	No	13.3	112,500	1.50 mm	0
20 May 24	ALPN Alpine Immune Sciences	Stock Option Common Stock	Sale back to company	Dispose D	No	No	13.2	70,155	926.05 k	0
20 May 24	ALPN Alpine Immune Sciences	Stock Option Common Stock	Sale back to company	Dispose D	No	No	3.23	26,922	86.96 k	0
20 May 24	ALPN Alpine Immune Sciences	Stock Option Common Stock	Sale back to company	Dispose D	No	No	4.09	2,635	10.78 k	0
8 May 24	ALPN Alpine Immune Sciences	Common Stock	Option exercise	Acquire M	No	No	4.76	10,000	47.60 k	133,392
8 May 24	ALPN Alpine Immune Sciences	Common Stock	Option exercise	Acquire M	No	No	3.23	38,078	122.99 k	123,392

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.