Thank on you, you our thank Mike. us Good morning, for call joining everyone and today.
and number the generated the cash a a plans the in continued number optimization FTXXX, required legacy FTXXX; across complete As operational cost XXXX including: being and the has rapid organizational strategic people the deliver three, ensuring objectives our put we the great progress NDA actions; in we flow our progressed, make and business. that earlier provable focus a viable reduction place of hospital to two, timely, of restructuring we year by one, continued positive commercially and deal number communicated this on a and and substantial to
taken our savings. annualized in reduction restructuring $XX revenue and quarter in on track to while realize portfolio, between our from actions and cost to-date better-than-expected Specifically, helped saw cost million hospital million two, us $XX we
This of alternative investment the second the XXXX, combination cash, FTXXX, continued while by a of company's have Avadel accelerated stabilizing and well we bring this operational cost nominal the In FTXXX. better-than-expected was the positioned of and in our our half to to Through believe patients. we the demonstrated beyond, as balance performance progress to narcolepsy during aggressive in only much-needed health. we is therapeutic advancing this have continue quarter, work XXXX reductions financial that use of revenue and first
second Let's the review for of highlights the some quarter.
Regarding FTXXX, enrollment in continues the to with progress line plans. REST-ON study in our
of we half nearly As of have XXX second target the complete XX% enrollment. enrollment enrollment rate, to of in Based randomized the we subjects, remain or on track on today, our current XXXX.
we advance discuss of Dr. support will Clinical President FTXXX, Jordan in FTXXX recently Seiden, Senior on Chief of our the key appointment moments. and these Medical In as Clinical Dave Wells, medical as and the to and our Vice update Medical strengthen have Jordan Medical Operations; few as Director, the Courtney Development an as well appointments provide Dr. significantly clinical Officer, with a appointment of announced as and efforts team, Dubow, Affairs. program
is team to medical impact and on an clinical new the program. Our FTXXX already beginning make
in their look in comprehensive and contributions to bringing confident a are and expeditious the and forward both to manner. market We FTXXX team's to impact
payers, XXXX once-nightly as well care The ways. the as work Patients, in to some contribution demonstrated in all potential the in of of the itself a of data to patient of to manifest which recently high This importance narcolepsy a treatment. we degree SLEEP value pharmacokinetic, conducted expressed PK, was have the oxybate a space, in highlighted doctors FTXXX or have potential differentiate conference. presented interest sodium continues also many at in and was FTXXX
our gram study data comparison head-to-head once nightly PK immediate-release X.X sodium oxybate. We FTXXX a X.XX to from presented of grams twice of nightly
a three data data demonstrated which increasing or concentrations presented measured compared demonstrated proportionality we FTXXX. dose the oxybate. peak FTXXX's under This across twice-nightly and total of linearity drug from doses study, once overall when area lower to similar by AUC exposure addition, sodium as In plasma nightly curve
and like over call FTXXX, the share further our I'd turning current Before for highlights to on Jordan operational update financial on some to position.
restructuring we to quarter in one we the yielded achieve. initiated sought has major the results First,
$XX annualized to Our SG&A to continue expenses savings. are in to $XX already realize million we noted, expect cost substantially down million as year-over-year. And
focused flow cash Secondly, products on hospital our and we remain from maximizing business. the opportunity
on existing be in excess had of of Based performance business half revenue ahead to which of is guidance, another expect XXXX the we the For legacy the full million. now to first hospital year, previous quarter. year strong well products, $XX
previously approved expectation and our on maintain It given forward. downward competitors business new this is note of important revenues for to assumed the the that pressure pricing and and we going nature increasing
position manage defend As expenses FTXXX. their we margin have in of to both will we done in respective and the support and the development to that positive ensure markets, flow to of our business each while continue continues cash the past, aggressively generate we carefully
discretion is new from review FDA which had the was the FDA's in provided. NDA additional extend extended data ongoing or during assigned had accepted We its NDA. extension XX an date submitted information requested company we and by for submitted requested This data March action are the the December as their PDUFA date related and to and original was September to on the the the of Furthermore, information when by XX. with to of the shared PDUFA the PDUFA FDA deadline yesterday XX AVXXX, date it
our is strength our in three-month that of contribute NDA our in point the timing planned It provided. It first in is the if XXXX. to to we've changes the approved important begin revenues the commercial quarter out including will that data launch additional we expectation to this have or submitted, no belief of way package extension AVXXX
I Avadel am a is that pleased entering report than was different to company XXXX. what to-date, very it
improved that a financial health, changes development contributed believe significant organizational which of to to which our our series a $X continues position has of had further potential disruptive the billion plus and undergone in FTXXX, have drive all of we focus to us We market.
With that, further Dubow, like FTXXX call over to program. to Chief on Officer Jordan? I'd our to provide turn the Dr. the Medical Jordan commentary