everyone. Thank you, good And Chris. afternoon
Please with let call today's basis, many well on information financial started www.nuvasive.com further unless financial on covered as the get today's for as news are the of remind we to me noted Before financials, information refer non-GAAP reconciliations. in you otherwise. release supplemental measures a earnings regarding the that non-GAAP
NuVasive's a growth revenue on This X.X% and a grew strong portfolios. continues international. XXXX and Materials quarter Science fourth hardware to revenue hold million. reported adoption to was X.X% realization surgeon X.X% year-over-year, to we of was by market through driven procedure basis. $XXX.X performance implant product the across as on attributed continued spinal differentiated various constant around steady currency million, $XXX.X US take basis For is strategy up and hardware US system see This XXXX, implants. pull year-over-year above our Advanced
saw at growth growth outcome where targeted percent strategic Revenue single-digit of in low NuVasive from as our surgical prior year. historically revenue billing support An in $XX.X within increase cervical US million, under-penetrated. was a execution Service's segments We portfolio. resulting X.X% digit been open surgery have expected. Surgical spine support Clinical attributed in normalizing, to and came up over collections also mid-single we
to nearly the up return prior period. year in growth fourth over Biologics quarter, the X%
and to as synthetic We are as turn to portfolio see BBM include expand biologic headwinds. the corner we the well biologics annualizing offerings, price pleased mix to as have and worked competitive
Turning to We performance look This XX.X% was $XX.X this by for international, to forward revenue on fourth continue constant year-over-year in elevating a portfolios with than basis, NuVasive and XX.X% was XXXX, quarter year-over-year basis. growing pediatric more spine, a contributions orthopedic year-over-year as XX% currency region. growing on across reported, currency all and led regions. Europe specialized the constant million geographic
in performed the quarter in as digits the with high forward growing single made line XXXX. issue constraint set was in expectations, progress Asia-Pacific improve to internal
Mexico solid growth grew by currency the the primarily set in Latin availability of as constant in improved the half America basis, year. a mid On and throughout driven Brazil back double-digits,
pleased how at with business the year, our end ended the the range. guidance finishing international are of we Overall, upper
reserves new XX.X% point the margin or non-GAAP by Turning of as gross year as quarter product was driven manufacturing introductions. to operations, prior across a Gross well to basis of of improvement P&L, timing inventory was the XX.X%. for XXX expansion rest the efficiencies over fourth margin related
investments in based to SM&A XX% $XXX increased adjustments year, the in XX% medical quarter stock related to Pulse driven quarter primarily research revenue device X% over the expenses and year supply innovation investments by XX.X% The compared fourth increase XXXX. to fourth or in prior by development European The Non-GAAP totaled expenses million. increase costs, driven approximately revenue reflects in compensation increase primarily robotics. and from million, XXXX. price initiatives, R&D Non-GAAP mark-to-market $XX.X of or were stock of remaining or Pulse relates and of chain the by in expenses. our the Approximately revenue prior X.X% of X%
mentioned spending, in Fourth stock the XXXX based at was partially quarter insource came XX margin over prior by previously driven offset non-GAAP by and basis disciplined XX.X%, increase an operating manufacturing year. points compensation efficiencies of from primarily This headwind.
fourth $XX.X in million, XX.X%. Turning discreet non-GAAP effective diluted for adjustments our a rate in in lower for the non-GAAP the tax diluted $X.XX share Fourth quarter net one non-GAAP quarter compared non-GAAP non-GAAP last of expected tax reflects $X.X a income tax, the rate period. tax of net than per favorable million, earnings or time, non-GAAP This of million to the to EPS income expense of period year. was was resulting couple same of $X.XX $XX.X quarter or
net Turning our to quarter diluted earnings $X.XX same million period year. share million, of GAAP $XX.X were or of results, EPS GAAP diluted to last the of earnings the $XX.X or GAAP for GAAP XXXX fourth $X.XX compared per in
discuss a guidance. our Now quick of before I review XXXX year XXXX numbers full
Non-GAAP margin $XXX a in streamlining a offset efficiencies. prior year of basis gross previously Operating billion, by X% As expansion year to prior revenue XX.X%, full operating non-sales reported or was functions reinvestments constant and above on benefits margin margin business. in areas office of was and X.X% currency with primarily on growing XX.X% key as at back strategic for margin the driven basis, compared improvement, manufacturing Non-GAAP from the Chris the in a by stated, XX.X% was partially expansion gross by year. XXX basis. points driven and year came
in $XX.X compared prior EPS Full XX.X% diluted of our non-GAAP year full tax year, $XXX.X or $X.XX the diluted Non-GAAP and increase of per rate was million, net an year. was income other of was earnings and non-GAAP million, for non-GAAP XX.X%. $X.XX, expense share to income effective the
cash higher million, cash flow the to for was With million up million, XXXX over $XXX.X guidance for decrease and be and inventory growth cash free of $XXX.X regard to by in year for year. expenditures XXXX. driven year from Finally, The was our we equivalents prior X% estimate revenue instrument year to the by our was $XX.X million full range compared X%. for performance, XXXX, Year-end in to surgical prior operating $XXX sets. offset
immaterial expect currency an have to We impact.
these Let me within provide in provided expectations setting range. context some the
Our guidance reflects factors. a few internal macro and
expect remain XXXX. market experienced what rates to we to spine stable XXXX US to First, we at similar continue in in the
by implants. US for Materials XXXX spinal hardware driven trends Second, saw our the the of the line in we business system outlook remains with Science strong, XXXX, adoption similar Advanced and
low expect we international double sales the growth Third, digits. in
introductions X%, market to hardware driven the is adoption of grow XXXX on accelerated revenue training of spinal US and expected multiples by the at X% our product new to system.
for expand fully Coast We key training several capacity will the leverage East international. including and our best-in-class clinical by and locations, program surgeon development in expanding
to continue targeting market cervical TLIF, we where market open also an are we opportunity will traditional We and segments spine where deformity. surgery our focus gain like and have underrepresented, share, on
dozen We the respective products, continuing on the offering. new The and alpha year. to enabling look full first development a and will a implants the half competitive XXXX our of focus while about by these technology anticipated of in launches maintain products areas commercial in be commercialization launching half with instrumentation of back all
growing range positive decline at XXXX, US product realistic and historical This is also in don't and to continued IOM X% a to included tailwinds We believe pricing collections the continue. expect we range guidance comparisons lines based pressure is surgical on NCS that our this rate. biologics a X% which from of from growth. billing assumes tough support market
double strategy international international the continued digits. in of share XXXX, This to growth. product remains markets is going deeper business core For new is introductions driving for key grow taking on the delivering expected and our low predicated at
be line XXXX XXXX, plus what XX.X%. the with to of in and of This in expect last infrastructure, our Day packaging Moving at we operating XX.X% operating device range XX% European year's margin Investor the in we invest margin to by on is regulation for medical communicated XXXX. strategy our to driving to In must deliver sterile years. future we non-GAAP in growth and operating margin,
be achieve cadence heavily we the annualization and expect some our to year half contraction the to the second In XXXX. to year timing of we made stock clear, in terms expect fiscal first it investments half and of guidance. back margin and of of due in the throughout based the margin timing of of expansion XXXX, of growth, to half To year compensation, weighted be
year The to $X.XX range This repeat. company to a basis, one-time for from don't that diluted full several in we of diluted XXX. estimates expect of share share in non-GAAP headwinds the reflects to XXXX XXX GAAP range per a in XXXX earnings the per range we tax items estimate favorable $X.XX. On earnings
Relations press nuvasive.com on section on can today's or in Investor further expectations You find the GAAP details our release. in
One on capital than guidance, we capital by million, expenditures. driven which to free associated due increase to the increase an flow, expenditures This in education cash our cash disclosed headquarters improved Diego remains operating previous at is in flow, flow be investments expect free capital With final and by cash $XXX roadmap, be item San same. in the greater offset will instruments our allocation with manufacturing strong surgical new our primarily operations. facility packaging surgeon sterile strategy
will M&A, in potential balance we share We infrastructure program. continue repurchases well and to our also assets procedural under company will consider as and repurchase authorized our opportunistic as R&D, investments
in in to the make supply come. market, to to to in globalization performance positive NuVasive's patients' lives to XXXX, believe be and leading conclusion, we to thrive continue In in European and innovator improved foundational increase In that disruptive the remain investments chain and technology plan R&D ability to invest years initiatives operational We will spend predictable the outcomes. drive in on I drive enabling and spine. competitive enables technology changes efficiency
the growth you. these margin I and future. am through into expansion the returns Thank revenue investments significant confident will to company drive
Q&A I'd like to with And begin that, session. the