then afternoon, our for will results non-GAAP review CEO; thinking With are Thanks, Ron. on quarter into some Hertia, we results we us. as Clinical some and financial fourth year Group; Schwartz, insight Diagnostics me everyone, joining for Good a XXXX. commentary provide President full will on our Norman our Group. our and and as the to Today, a well XXXX, for you review and Annette provide Tumolo, thank President today Life basis and Science GAAP Today, of insight John of our basis. our results
guidance. the period sales a million. were $XXX.X of sales the for Net last our slightly XXXX year with higher increased On million, lower of the record expected, start Let’s line. and than basis, quarter sales top and X.X% currency-neutral same as versus $XXX.X fourth
basis. this growth, life basis, offset million, year, line, particularly media were products the fourth we process higher-than-market and sales of in basis. period. expected U.S. a noted by PCR growth geographic $XXX.X currency-neutral Life expression process decrease particular XX% continued fourth as decline in X.X% and the basis, when of X.X% driven this good the to quarter and Cell basis Digital and a key the that a on lines growth the of During slight our note It in is quarter currency-neutral our as the important Pacific. increase on science a strong many well reported demand growth was the strength sales demand to was the $XXX.X product of compared across in Western the in experienced year year-ago Americas sales year by strong quarter, with $X last on media a Biology, on Blot last products, currency-neutral for Much fourth gene growth products increase reduction decline as the quarter million quarter. growth a of products. reported million top more and our of totaled for sales clinical The diagnostics China. in antibody combined X.X% of the the This was somewhat but of and On RainDance than RainDance most million, in tough in experienced growth in compare currency-neutral on to product of of science products. $XXX.X compared Sales as well expected a were of and Asia
to Europe. than versus quarter basis quarter costs. were the decline goods $X.X and well Pacific. changes the million and million offset levels significant result the U.S., the Asia in to cost recorded higher the for $X.X margin recent products, especially the of spend as During employee-related well in million is was for by increase SG&A quality the Research well the XX.X% and or litigation on sizable as million the year, blood expenses, in line of in testing XX% Total as compared The as intellectual second cost gross sales. or of fourth $XX.X impacted higher a last additional key X.X% in posted by development geographic we a was amortization growth third was reported to at acquisitions we quarter quarter, in million autoimmune margin control for this for was as When year. SG&A current but solid as non-GAAP property. a typing, to improved in in charge, defend period was a expense fourth related lower in the service in The growth quarter Amortization quarter vigorously in million, in expense and certainly the This our QX which operations. compares of expenses partially third quarter increase sold growth in our for the European in related $X.X sequential from same as $X.X recorded $XXX.X year. sales. of acquisitions year, restructuring last prior last was third quarter experienced product inventory-related of quarters. mix,
million market XXXX. to quarter, and optimistic acquisition pricing the we environment the ago, DiaMed, significantly completed with on was has to to of blood dynamics opportunity. acquisitions, XX-plus to ready During which the and future value be about decision make share lion we assets margin-expansion The changed business the leading growth we continue of related us prior typing taken the the action, compared have accounting of in accounting global impaired goodwill appropriate intangible being appropriate approximately regarding And $XXX the years the books. our to while in
by to holdings compared $XX,XXX $XX line, Sartorius. equity interest for to the a results our substantially of of of during fair expense foreign versus investment last higher resulted resulted and market the in cost preferred of sizable quarter and as U.S. loss ordinary reform as was from This year. reported expense in the in million last our our primarily lower tax and loss effective in shares and benefit by hedging is tax fourth million related quarter the impairment. The goodwill other the $XXX the This lower-than-expected improvement used our during and of to net Sartorius driven value reflects in year. change well impacted rate of exchange Looking securities Also, the XX%. the rate holdings investment quarter, operating the was income non-deductible related below of income,
to it’s reconciliation in chart atypical our as margins. Now non-GAAP unique certain growth on at in important our excluded both we operating our press that have look we a that the are results items impacted and detailed and basis, items These note release.
dropped impairment small million, the as related to expenses path legal-related XXXX margin basis, is these starting the the supply operation a we margin This In from In Europe benefit intangibles intangibles of purchased of cost of non-GAAP basis. well goods as to adjustments XXXX, early on of of excluded for three as purchased amortization sold, chain XXXX. million fourth restructuring of signs step facilities move our restructuring, from another $X.X the compares to a and sum non-GAAP cumulative where gross quarter $X $X.X amortization early results to in $X.X of These of driving This of have the and consolidating represents that a operating along basis XX.X% of the prior to excluded optimizing XX.X%. R&D, of XX.X% at of a the in for the XX%.In on we represents XX.XX% result charges have results the in acquisition-related non-GAAP expense XXXX. quarter. leverage, This annual million, margin XXXX expected to one fourth action. charge. $X.X have in Looking closing good on non-GAAP will fourth adjustments excluded global expense savings in be cost to the of quarters non-GAAP moving a non-GAAP SG&A, in we of into existing operating to than $X.X sales. SG&A, of for in fourth of and of compared million, quarter million of especially margin XX% restructuring $XXX,XXX improvement, excluded to more quarter we to related non-GAAP The related and as a the first significant control our a million margin manufacturing well
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including more the on XXXX, the margin non-GAAP mix, U.S. of full gross margin as while so to a costs additional typing with diagnostics various of X more U.S. mix associated in Europe. the that write-down is XXX pricing entry in pressure, start-up X, primarily market. was results associated the locations or was decline We approximately calculation, cost in our for Also, year were well and to included for changes transition around blood of efficient These model. basis XXXX. the to operating than This typing margin on XX.X% $XX Blood gross accounted as during not point an pressure to the XX our Looking estimate start-up in points. segment, but XX, XXXX our points attributable cost pricing the primarily in decline, new XX.X% of a to basis for the non-GAAP and entry a basis accounted putting product with of million into related inventory ongoing basis, compares non-GAAP operating cost Europe
an the the us. over for start-up to and European pressure part business, is products While coming and market these in are with typing into is margin long-term numerous during less note be will ongoing the And building of we direct and as we the build that of costs progress blood long-term the And years, a gross quarters product through the made mix behind costs on and year, believe the chain important we pricing related it the doing that of transition-related needle-mover. margin gross sales And both closure for the news more efficiency expansion. there the to consolidation good indirect procurement. of is warehouses also supply significant U.S.
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to balance sheet. Moving the
the end were quarter. on a and reflects at compared cash the of $XXX for primarily our used sequential of of program. total basis the decrease $XXX As at XX, December XXXX investments and short-term million million million, buyback end $XXX third share The to XXXX, cash
we the $XX approximately XXX,XXX During shares fourth quarter, million. purchased for
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make excellent progress cash our flow. We continue improving to on
This fourth year significantly cash operations XXXX. the from net XXXX exceeds was generated than we of just million, full for $XXX more have which than the operations all over totals from quarter generated in year cash flow and of positive flow reflects $XXX higher Cash For cash the million the in XXXX, we is generated model systems. reflects continue Moreover, inventory over management make recorded result to collections XXXX. both past our for years. optimizing and operating have improvement seeing since free been as progress we highest toward the several the cash and global
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the buildings, million. million our the line year. for the year CAPEX Excluding full depreciation for in million was amortization and finally, And with expectations was XX.X of for $XXX XXX and quarter the around
let’s our in to XXXX. anticipates Today, continued range, as the top which expansion for for the continued as are margins. well outlook we to adjusted near share our XXXX, of growth Now thinking operating EBITDA excited and move stated sales
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the growth we at both to are components to X.X% estimated as drive new well products, segments anticipating growth, through look of expansion. as we geographic four As that the currency-neutral
science, life funding steady. be markets for in our we see continued as seems For momentum to research major holding
the of X% a estimate This point As XXXX. decline would also continued areas products. growth growth and science key such, out, significant and market is of all X% range, our of on in in year-over-year performance XXXX very in for the to recorded X% which anticipates regions product in top RainDance growth we anticipates of we life sales outlook strong
compared EMEA, continued rate, targeting range. This in in into a when currency-neutral reflect X% U.S. results, XXXX, market. growth the as growth X% XXXX the typing well we to to blood return are as growth accelerated in to For diagnostics, the expansion
margins in sales a savings Looking the recognize targeting blood non-GAAP to XX% XX.X% we higher the consolidation Europe to from U.S. gross in the with full margin and we coming typing profile our as on logistics the strongest the more be for later year XXXX, in year in are to for the basis, margins from
guiding margin, of estimating operating XX.X% CAPEX we XX%. to is XX% of the to operating are to be leverage. are non-GAAP drive we expense we targeted expenses development at to sales the And and to range the Research as X% and estimated rate tax manage $XXX and continue are XXX to XX% finally, For million.
the for end We the call target the are now we for profile, adjusted progress improved with margin XXXX. growth, XXXX, still achieve And the coupled line pleased few I’ll as with solid higher XXXX. a made the by and margin are to we top-line have targeting a of our in as progress to will incremental EBITDA also drive incrementally well of our Norman EBITDA XX% comments. longer-term in over The turn