|Kate Rausch||Head of Investor Relations|
|Paul Bolno||President & Chief Executive Officer|
|Chandra Vargeese||Chief Technology Officer|
|Mike Panzara||Chief Medical Officer, Head of Therapeutics Discovery & Development|
|Kyle Moran||Chief Financial Officer|
|Luca Issi||RBC Capital|
Good morning and welcome to the Wave Life Sciences Third Quarter 2021 Financial Results Conference Call. At this time, all participants are in a listen-only mode. After the speakers' presentation, there will be a question-and-answer session. [Operator Instructions] As a reminder, this call is being recorded and webcast. I will now turn the call over to Kate Rausch, Head of Investor Relations at Wave Life Sciences.