aTyr Pharma (ATYR)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	14.38 mm	14.38 mm	14.38 mm	14.38 mm	14.38 mm	14.38 mm
Cash burn (monthly)	(no burn)	(no burn)	6.05 mm	5.67 mm	4.39 mm	5.59 mm
Cash used (since last report)	n/a	n/a	32.05 mm	30.05 mm	23.24 mm	29.61 mm
Cash remaining	n/a	n/a	-17.67 mm	-15.67 mm	-8.86 mm	-15.23 mm
Runway (months of cash)	n/a	n/a	-2.9	-2.8	-2.0	-2.7

Beta Read what these cash burn values mean

Financial data from aTyr Pharma earnings reports.

Institutional ownership, Q4 2024

ATYR institutional ownership history Ownership history

71.8% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	83	61	+36.1%
Opened positions	30	14	+114.3%
Closed positions	8	6	+33.3%
Increased positions	24	15	+60.0%
Reduced positions	12	12	–

13F shares	Current	Prev Q	Change
Total value	196.96 bn	83.50 bn	+135.9%
Total shares	60.27 mm	53.26 mm	+13.2%
Total puts	40.30 k	3.10 k	+1200.0%
Total calls	51.10 k	30.20 k	+69.2%
Total put/call ratio	0.8	0.1	+668.3%

Largest owners	Shares	Value	Change
FHI Federated Hermes	14.67 mm	$53.09 bn	0.0%
FMR	12.10 mm	$43.79 bn	+6.4%
Point72 Asset Management	4.88 mm	$17.68 bn	NEW
Vanguard	3.60 mm	$13.05 bn	+20.7%
Tikvah Management	2.46 mm	$8.91 bn	0.0%
Woodline Partners	1.68 mm	$6.09 bn	-0.0%
Alta Partners VIII	1.59 mm	$11.04 mm	0.0%
BlackRock	1.53 mm	$5.52 bn	+9.2%
Aspire Capital Fund	1.31 mm	$8.18 mm	0.0%
Alyeska Investment	1.28 mm	$4.63 bn	-26.0%

Largest transactions	Shares	Bought/sold	Change
Point72 Asset Management	4.88 mm	+4.88 mm	NEW
Checkpoint Capital	432.56 k	-1.30 mm	-75.1%
Logos Global Management	1.00 mm	-1.00 mm	-50.0%
Citadel Advisors	12.36 k	-954.25 k	-98.7%
Octagon Capital Advisors	900.00 k	+900.00 k	NEW
Ghost Tree Capital	0.00	-800.00 k	EXIT
FMR	12.10 mm	+728.00 k	+6.4%
Ally Bridge	699.73 k	+699.73 k	NEW
Susquehanna International	787.84 k	+654.61 k	+491.3%
Vanguard	3.60 mm	+617.35 k	+20.7%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

ATYR insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
4 Feb 25	Denyes Nancy	Common Stock	Sell	Dispose S	No	No	3.78	899	3.40 k	26,555
4 Feb 25	Broadfoot Jill Marie	Common Stock	Sell	Dispose S	No	No	3.78	1,254	4.74 k	31,763
3 Feb 25	Denyes Nancy	Common Stock	Option exercise	Acquire M	No	No	0	2,687	0.00	27,454
3 Feb 25	Denyes Nancy	RSU Common Stock	Option exercise	Dispose M	No	No	0	2,687	0.00	2,687
3 Feb 25	Broadfoot Jill Marie	Common Stock	Option exercise	Acquire M	No	No	0	3,750	0.00	33,017
3 Feb 25	Broadfoot Jill Marie	RSU Common Stock	Option exercise	Dispose M	No	No	0	3,750	0.00	3,750
3 Feb 25	Shukla Sanjay	Common Stock	Option exercise	Acquire M	No	No	0	10,375	0.00	146,923
3 Feb 25	Shukla Sanjay	RSU Common Stock	Option exercise	Dispose M	No	No	0	10,375	0.00	10,375
8 Jan 25	Denyes Nancy	Employee Stock Option Common Stock	Grant	Acquire A	No	No	3.74	275,000	1.03 mm	275,000
8 Jan 25	Shukla Sanjay	Employee Stock Option Common Stock	Grant	Acquire A	No	No	3.74	1,000,000	3.74 mm	1,000,000