AnaptysBio (ANAB)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	109.83 mm	109.83 mm	109.83 mm	109.83 mm	109.83 mm	109.83 mm
Cash burn (monthly)	(no burn)	6.81 mm	(no burn)	5.41 mm	9.12 mm	12.08 mm
Cash used (since last report)	n/a	29.24 mm	n/a	23.24 mm	39.14 mm	51.86 mm
Cash remaining	n/a	80.59 mm	n/a	86.59 mm	70.69 mm	57.97 mm
Runway (months of cash)	n/a	11.8	n/a	16.0	7.8	4.8

Beta Read what these cash burn values mean

Financial data from AnaptysBio earnings reports.

Institutional ownership, Q4 2024

ANAB institutional ownership history Ownership history

13F holders	Current	Prev Q	Change
Total holders	145	170	-14.7%
Opened positions	28	43	-34.9%
Closed positions	53	13	+307.7%
Increased positions	51	61	-16.4%
Reduced positions	35	31	+12.9%

13F shares	Current	Prev Q	Change
Total value	438.89 bn	1.09 tn	-59.8%
Total shares	47.22 mm	45.69 mm	+3.3%
Total puts	2.35 mm	1.12 mm	+110.4%
Total calls	1.47 mm	829.10 k	+77.2%
Total put/call ratio	1.6	1.3	+18.7%

Largest owners	Shares	Value	Change
EcoR1 Capital	7.87 mm	$104.24 bn	+1.0%
EcoR1 Capital Fund	7.15 mm	$139.53 mm	0.0%
FMR	3.03 mm	$40.12 bn	-8.4%
BLK BlackRock	2.55 mm	$33.74 bn	+16.9%
Tang Capital Partners	1.95 mm	$46.68 mm	0.0%
Vanguard	1.84 mm	$24.41 bn	+8.4%
Fairmount Funds Management	1.82 mm	$24.05 bn	NEW
Frazier Life Sciences Management	1.57 mm	$20.84 bn	-28.8%
Tang Capital Management	1.33 mm	$17.62 bn	0.0%
Boxer Capital Management	1.30 mm	$17.21 bn	NEW

Largest transactions	Shares	Bought/sold	Change
Fairmount Funds Management	1.82 mm	+1.82 mm	NEW
Boxer Capital Management	1.30 mm	+1.30 mm	NEW
Boxer Capital	0.00	-1.30 mm	EXIT
Camber Capital Management	1.25 mm	+1.25 mm	NEW
SNY Sanofi	821.92 k	+821.92 k	NEW
Mangrove Partners	0.00	-689.52 k	EXIT
Frazier Life Sciences Management	1.57 mm	-635.47 k	-28.8%
Soleus Capital Management	414.00 k	+414.00 k	NEW
STT State Street	1.29 mm	+379.57 k	+41.9%
BLK BlackRock	2.55 mm	+368.28 k	+16.9%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

ANAB insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
15 Jan 26	Marquet Magda	Common Stock	Sell	Dispose S	No	No	48.849	1,710	83.53 k	9,930
15 Jan 26	Marquet Magda	Common Stock	Sell	Dispose S	No	No	48.1162	9,290	447.00 k	11,640
15 Jan 26	Marquet Magda	Common Stock	Option exercise	Acquire M	No	No	26.11	11,000	287.21 k	20,930
15 Jan 26	Marquet Magda	Stock Option Common Stock	Option exercise	Dispose M	No	No	26.11	11,000	287.21 k	0
8 Jan 26	Daniel Faga	Common Stock	Sell	Dispose S	No	No	44.71	14,281	638.50 k	479,344
8 Jan 26	Loumeau Eric J	Common Stock	Sell	Dispose S	No	No	44.71	2,210	98.81 k	12,835
8 Jan 26	Mulroy Dennis	Common Stock	Sell	Dispose S	No	No	44.71	2,515	112.45 k	21,852
8 Jan 26	Lizzul Paul F.	Common Stock	Sell	Dispose S	No	No	44.71	3,650	163.19 k	42,088
7 Jan 26	Daniel Faga	Common Stock	Option exercise	Acquire M	No	No	0	26,838	0.00	493,625
7 Jan 26	Daniel Faga	RSU Common Stock	Option exercise	Dispose M	No	No	0	26,838	0.00	80,512

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.