| Quarter (USD) | Dec 24 | Sep 24 | Jun 24 | Mar 24 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Annual (USD) | Dec 24 | Dec 23 | Dec 22 | Dec 21 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Cash burn rate (est.) | Burn method: Change in cash | Burn method: Operating income | Burn method: FCF (opex + capex) | Last Q | Avg 4Q | Last Q | Avg 4Q | Last Q | Avg 4Q |
|---|---|---|---|---|---|---|
| Cash on hand (at last report) | 399.76 mm | 399.76 mm | 399.76 mm | 399.76 mm | 399.76 mm | 399.76 mm |
| Cash burn (monthly) | (no burn) | (no burn) | 8.52 mm | 13.77 mm | 9.61 mm | 10.18 mm |
| Cash used (since last report) | n/a | n/a | 20.26 mm | 32.75 mm | 22.86 mm | 24.22 mm |
| Cash remaining | n/a | n/a | 379.50 mm | 367.00 mm | 376.90 mm | 375.54 mm |
| Runway (months of cash) | n/a | n/a | 44.5 | 26.6 | 39.2 | 36.9 |
| 13F holders | Current |
|---|---|
| Total holders | 200 |
| Opened positions | 57 |
| Closed positions | 10 |
| Increased positions | 56 |
| Reduced positions | 59 |
| 13F shares | Current |
|---|---|
| Total value | 2.99 tn |
| Total shares | 157.05 mm |
| Total puts | 298.40 k |
| Total calls | 1.32 mm |
| Total put/call ratio | 0.2 |
| Largest owners | Shares | Value |
|---|---|---|
| Growth Equity Opportunities Fund IV | 44.68 mm | $452.59 mm |
| Vivo Ventures VI | 23.49 mm | $157.88 mm |
| Vivo Ventures Vii | 20.25 mm | $692.44 mm |
| Perceptive Advisors | 6.39 mm | $296.85 bn |
| NEA Management | 5.58 mm | $259.36 bn |
| Frazier Life Sciences Management | 3.38 mm | $157.15 bn |
| Eventide Asset Managment | 3.13 mm | $145.46 bn |
| Maverick Capital | 3.13 mm | $145.29 bn |
| Wellington Management | 3.03 mm | $140.49 bn |
| Vivo Capital | 2.28 mm | $106.07 bn |
| Date | Owner | Security | Transaction | Code | Indirect | 10b5-1 | $Price | #Shares | $Value | #Remaining |
|---|---|---|---|---|---|---|---|---|---|---|
| 26 Feb 25 | David R Ebsworth | Ordinary Shares | Gift | Dispose G | No | No | 0 | 64,000 | 0.00 | 1,336,003 |
| 26 Feb 25 | David R Ebsworth | Ordinary Shares | Option exercise | Acquire M | No | No | 1.9338 | 100,000 | 193.38 k | 1,400,003 |
| 26 Feb 25 | David R Ebsworth | Ordinary Shares | Option exercise | Acquire M | No | No | 2.67 | 96,000 | 256.32 k | 1,300,003 |
| 26 Feb 25 | David R Ebsworth | Ordinary Shares | Option exercise | Acquire M | No | No | 0.5038 | 200,000 | 100.76 k | 1,204,003 |
| 26 Feb 25 | David R Ebsworth | Ordinary Shares | Option exercise | Acquire M | No | No | 0.775 | 64,000 | 49.60 k | 1,004,003 |
| 26 Feb 25 | David R Ebsworth | Share Option (Right to Exercise) Ordinary Shares | Option exercise | Dispose M | No | No | 1.9338 | 100,000 | 193.38 k | 140,000 |
| 26 Feb 25 | David R Ebsworth | Share Option (Right to Exercise) Ordinary Shares | Option exercise | Dispose M | No | No | 2.67 | 96,000 | 256.32 k | 0 |
| 26 Feb 25 | David R Ebsworth | Share Option (Right to Exercise) Ordinary Shares | Option exercise | Dispose M | No | No | 0.5038 | 200,000 | 100.76 k | 0 |
| 26 Feb 25 | David R Ebsworth | Share Option (Right to Exercise) Ordinary Shares | Option exercise | Dispose M | No | No | 0.775 | 64,000 | 49.60 k | 0 |
| 3 Feb 25 | Kathleen A. Rickard | Ordinary Shares | Payment of exercise | Dispose F | No | No | 7.1625 | 33,240 | 238.08 k | 2,688,240 |
