| Quarter (USD) | Sep 24 | Jun 24 | Mar 24 | Dec 23 | |
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| Change in cash | |||||
| Diluted EPS |
| Annual (USD) | Dec 23 | Dec 22 | Dec 21 | Dec 20 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
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| Diluted EPS |
| 13F holders | Current |
|---|---|
| Total holders | 284 |
| Opened positions | 53 |
| Closed positions | 17 |
| Increased positions | 104 |
| Reduced positions | 88 |
| 13F shares | Current |
|---|---|
| Total value | 4.87 tn |
| Total shares | 29.81 mm |
| Total puts | 363.60 k |
| Total calls | 482.90 k |
| Total put/call ratio | 0.8 |
| Largest owners | Shares | Value |
|---|---|---|
| FMR | 4.29 mm | $781.43 bn |
| BlackRock | 3.99 mm | $726.87 bn |
| Vanguard | 2.85 mm | $518.74 bn |
| Avoro Capital Advisors | 2.62 mm | $477.32 bn |
| STT State Street | 1.45 mm | $264.46 bn |
| Frazier Life Sciences Management | 988.46 k | $179.93 bn |
| Sun Pharma | 914.11 k | $78.12 mm |
| Frazier Life Sciences IX | 895.00 k | $53.70 mm |
| Capital World Investors | 879.08 k | $160.02 bn |
| Redmile | 810.25 k | $147.49 bn |
| Date | Owner | Security | Transaction | Code | Indirect | 10b5-1 | $Price | #Shares | $Value | #Remaining |
|---|---|---|---|---|---|---|---|---|---|---|
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | No | 171.6245 | 620 | 106.41 k | 1,475,882 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 170.4303 | 727 | 123.90 k | 1,476,502 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 169.4802 | 953 | 161.51 k | 1,477,229 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 168.3103 | 200 | 33.66 k | 1,478,182 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 166.9582 | 798 | 133.23 k | 1,478,382 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 165.7947 | 2,114 | 350.49 k | 1,479,180 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 164.915 | 4,723 | 778.89 k | 1,481,294 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 163.9154 | 8,923 | 1.46 mm | 1,486,017 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | Yes | Yes | 163.0435 | 5,942 | 968.80 k | 1,494,940 |
| 13 Dec 24 | Krish S Krishnan | Common Stock | Sell | Dispose S | No | Yes | 171.6288 | 640 | 109.84 k | 1,537,262 |
